SCHEMBL840786

SCHEMBL840786

CCCCCCOCCOCCOCCOCCOCCOCCOc1ccc(O)cc1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.83
LTA4H P09960 3/20 0.72
LMNA P02545 2/20 0.59
MEN1 O00255 1/20 0.59
USP2 O75604 1/20 0.59
ALDH1A1 P00352 1/20 0.59
CYP3A4 P08684 1/20 0.59
MAPK1 P28482 1/20 0.59
CASP1 P29466 1/20 0.59
KMT2A Q03164 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
SLCO1B3 Q9NPD5 1/20 0.59
SLCO1B1 Q9Y6L6 1/20 0.59
RARB P10826 3/20 0.55
TP53 P04637 2/20 0.54
TSHR P16473 1/20 0.54
PLA2G4B P0C869 2/20 0.53
APP P05067 1/20 0.51
NPC1 O15118 1/20 0.50
GAA P10253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL840785 1.00 NR5A1 (0.83) NR5A1LTA4HLMNAMEN1USP2
SCHEMBL14566123 1.00 NR5A1 (0.83) NR5A1LTA4HLMNAMEN1USP2
SCHEMBL10357881 1.00 NR5A1 (0.83) NR5A1LTA4HLMNAMEN1USP2
SCHEMBL6939767 0.95 NR5A1 (0.75) NR5A1LTA4HLMNAMEN1USP2
SCHEMBL2364499 0.95 NR5A1 (0.86) NR5A1LTA4HLMNAMEN1USP2
SCHEMBL9016366 0.95 LTA4H (0.72) NR5A1LTA4HLMNAMEN1USP2
SCHEMBL337790 0.91 NR5A1 (1.00) NR5A1LTA4HLMNARARBTP53
SCHEMBL1834632 0.91 NR5A1 (1.00) NR5A1LTA4HLMNARARBTP53
SCHEMBL1401769 0.91 NR5A1 (1.00) NR5A1LTA4HLMNARARBTP53
SCHEMBL337505 0.91 NR5A1 (1.00) NR5A1LTA4HLMNARARBTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1651163-B1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME BIOCON LTD (IN) 2015-03-04 EP disclosed
US-8143366-B2 Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2012-03-27 US disclosed
US-8143366-B2 Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2012-03-27 US disclosed
US-8143366-B2 Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2012-03-27 US disclosed
US-20100081782-A1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME EKWURIBE NNOCHIRI N 2010-04-01 US disclosed
US-20100081782-A1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME EKWURIBE NNOCHIRI N 2010-04-01 US disclosed
US-20100081782-A1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME EKWURIBE NNOCHIRI N 2010-04-01 US disclosed
US-7625995-B2 Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2009-12-01 US disclosed
US-7625995-B2 Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2009-12-01 US disclosed
US-7625995-B2 Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2009-12-01 US disclosed
US-20080146778-A1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME BIOCON LIMITED (IN) 2008-06-19 US disclosed
US-20080146778-A1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME BIOCON LIMITED (IN) 2008-06-19 US disclosed
US-20080146778-A1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME BIOCON LIMITED (IN) 2008-06-19 US disclosed
EP-1651163-A4 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME BIOCON LTD (IN) 2008-03-26 EP disclosed
US-7335751-B2 Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2008-02-26 US disclosed
US-7335751-B2 Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2008-02-26 US disclosed
US-7335751-B2 Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2008-02-26 US disclosed
US-20060167234-A1 Aryl carbamate oligomers for hydroilyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2006-07-27 US disclosed
EP-1651163-A2 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME Nobex Corporation (US) 2006-05-03 EP disclosed
WO-2005016240-A2 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME NOBEX CORPORATION (US) 2005-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060167234-A1 Aryl carbamate oligomers for hydroilyzable prodrugs and prodrugs comprising same ALK, OGFR, AOX1 NR5A1 3682/4885LTA4H 606/4885LMNA 2670/4885
US-20080146778-A1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME ALK, AOX1, OGFR NR5A1 3633/4885LTA4H 505/4885LMNA 2294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.