Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL5679465 | 0.93 | ALDH1A1 (0.39) | ALDH1A1MAPTKEAP1NFE2L2KMT2A | |
| Hydrochloric Acid SCHEMBL3801844 | 0.92 | MEN1 (0.36) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| Sulfuric Acid SCHEMBL11340876 | 0.85 | ALDH1A1 (0.36) | ALDH1A1MAPTKMT2ALMNANPSR1 | |
| Trifluoromethanesulfonic Acid SCHEMBL8379815 | 0.83 | KCNH2 (0.36) | ALDH1A1MAPTKMT2ATSHRLMNA | |
| Trifluoromethanesulfonic Acid SCHEMBL11071110 | 0.82 | PTGS1 (0.34) | ALDH1A1MAPTTSHRLMNANPSR1 | |
| SCHEMBL5665263 | 0.81 | MAPT (0.43) | ALDH1A1MAPTLMNAHTTNPSR1 | |
| Zinc Ion SCHEMBL11063710 | 0.80 | MAPT (0.42) | ALDH1A1MAPTLMNAHTTNPSR1 | |
| SCHEMBL11063706 | 0.80 | MAPT (0.42) | ALDH1A1MAPTLMNAHTTNPSR1 | |
| Hydrochloric Acid SCHEMBL9464793 | 0.80 | MAPT (0.42) | ALDH1A1MAPTLMNAHTTNPSR1 | |
| SCHEMBL11068289 | 0.80 | POLB (0.35) | ALDH1A1MAPTTSHRLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656551-A1 | LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR | Honeywell International Inc. (US) | 2006-05-17 | — | — | EP | claimed |
| WO-2005019816-A1 | LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR | HONEYWELL INTERNATIONAL, INC. (US) | 2005-03-03 | — | — | WO | claimed |
| US-20050042758-A1 | Leak detection method using microencapsulated dye precursor | HONEYWELL CORPORATION | 2005-02-24 | — | — | US | claimed |
| EP-1421447-A4 | IMAGEABLE COMPOSITION CONTAINING INFRARED ABSORBER WITH COUNTER ANION DERIVED FROM A NON-VOLATILE ACID | KODAK POLYCHROME GRAPHICS LLC (US) | 2006-09-06 | — | — | EP | disclosed |
| US-7056639-B2 | Imageable composition containing an infrared absorber with counter anion derived from a non-volatile acid | EASTMAN KODAK COMPANY (US) | 2006-06-06 | — | — | US | disclosed |
| EP-1656551-A1 | LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR | Honeywell International Inc. (US) | 2006-05-17 | — | — | EP | disclosed |
| US-6921620-B2 | Acid curable composition of an acid generator; an infrared absorber; and optional colorant | KODAK POLYCHROME GRAPHICS LLC (US) | 2005-07-26 | — | — | US | disclosed |
| US-20050079439-A1 | Imageable composition containing an infrared absorber with counter anion derived from a non-volatile acid | KODAK POLYCHROME GRAPHICS LLC (US) | 2005-04-14 | — | — | US | disclosed |
| WO-2005019816-A1 | LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR | HONEYWELL INTERNATIONAL, INC. (US) | 2005-03-03 | — | — | WO | disclosed |
| US-20050042758-A1 | Leak detection method using microencapsulated dye precursor | HONEYWELL CORPORATION | 2005-02-24 | — | — | US | disclosed |
| US-6821583-B2 | SUBSTRATE WITH A CROSSLINKED LAYER DISPOSED ON IT HAVING AN IMAGEABLE INK-RECEPTIVE LAYER THAT IS ABLATION FREE | KODAK POLYCHROME GRAPHICS LLC | 2004-11-23 | — | — | US | disclosed |
| US-6783911-B2 | POSITIVE WORKING; HYDROXYFUNCTIONAL RESIN COMPRISING A COVALENTLY BOUND RADIATION SENSITIVE GROUP CAPABLE OF INCREASING THE SOLUBILITY OF SAID IMAGEABLE COMPOSITION IN AN ALKALINE DEVELOPER UPON EXPOSURE TO RADIATION | KODAK POLYCHROME GRAPHICS LLC | 2004-08-31 | — | — | US | disclosed |
| EP-1421447-A1 | IMAGEABLE COMPOSITION CONTAINING INFRARED ABSORBER WITH COUNTER ANION DERIVED FROM A NON-VOLATILE ACID | Kodak Polychrome Graphics LLC (US) | 2004-05-26 | — | — | EP | disclosed |
| US-20040009363-A1 | Substrate with a crosslinked layer disposed on it having an imageable ink-receptive layer that is ablation free | KODAK POLYCHROME GRAPHICS, L.L.C. (US) | 2004-01-15 | — | — | US | disclosed |
| US-20030194635-A1 | Isocyanate crosslinked imageable compositions | KODAK POLYCHROME GRAPHICS, L.L.C. | 2003-10-16 | — | — | US | disclosed |
| US-20030129526-A1 | Containing acid curable polymer, acid generator and infrared radiation absorberr | KODAK POLYCHROME GRAPHICS, L.L.C. | 2003-07-10 | — | — | US | disclosed |
| US-20030113655-A1 | Acid curable composition of an acid generator; an infrared absorber; and optional colorant | KODAK POLYCHROME GRAPHICS, L.L.C | 2003-06-19 | — | — | US | disclosed |
| WO-2003019294-A1 | IMAGEABLE COMPOSITION CONTAINING INFRARED ABSORBER WITH COUNTER ANION DERIVED FROM A NON-VOLATILE ACID | KODAK POLYCHROME GRAPHICS, L.L.C. (US) | 2003-03-06 | — | — | WO | disclosed |