Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL5679465 | 0.92 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1GAAPDGFRA | |
| Sulfuric Acid SCHEMBL5679463 | 0.92 | ALDH1A1 (0.39) | MEN1KMT2APOLBALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL9464793 | 0.88 | MAPT (0.42) | POLBALDH1A1GAAMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8082567 | 0.87 | MAPT (0.44) | POLBALDH1A1GAAMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11147817 | 0.87 | MAPT (0.41) | POLBALDH1A1GAAMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11147802 | 0.87 | MAPT (0.41) | POLBALDH1A1GAAMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11359417 | 0.87 | MAPT (0.41) | POLBALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL5665263 | 0.86 | MAPT (0.43) | POLBALDH1A1GAAMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11359415 | 0.86 | MAPT (0.43) | POLBALDH1A1GAAMAPTL3MBTL1 | |
| Zinc Ion SCHEMBL11063710 | 0.85 | MAPT (0.42) | POLBALDH1A1GAAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230378532-A1 | PolyElectrolyte Composition and Methods of Preparation Thereof | Kraton Corporation (US) | 2023-11-23 | — | — | US | disclosed |
| EP-4280332-A1 | POLYELECTROLYTE COMPOSITION AND METHODS OF PREPARATION THEREOF | Kraton Polymers Nederland B.V. (NL) | 2023-11-22 | — | — | EP | disclosed |
| EP-4234593-A1 | STYRENIC BLOCK COPOLYMERS AND METHODS OF PREPARATION THEREOF | Kraton Polymers Nederland B.V. (NL) | 2023-08-30 | — | — | EP | disclosed |
| US-20230265278-A1 | Styrenic Block Copolymers and Methods of Preparation Thereof | Kraton Corporation (US) | 2023-08-24 | — | — | US | disclosed |
| US-20210355342-A1 | BIO-SECURE PROTECTIVE EQUIPMENT AND METHODS FOR MAKING | KRATON POLYMERS LLC (US) | 2021-11-18 | — | — | US | disclosed |
| WO-2021212147-A2 | BIO-SECURE PROTECTIVE EQUIPMENT AND METHODS FOR MAKING | KRATON POLYMERS LLC (US) | 2021-10-21 | — | — | WO | disclosed |
| US-8703092-B2 | Type separation of single-walled carbon nanotubes via two-phase liquid extraction | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-04-22 | — | — | US | disclosed |
| US-20100166637-A1 | Type Separation of Single-Walled Carbon Nanotubes via Two-Phase Liquid Extraction | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2010-07-01 | — | — | US | disclosed |
| WO-2008057070-A2 | TYPE SEPARATION OF SINGLE-WALLED CARBON NANOTUBES VIA PHASE TRANSFER | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-05-15 | — | — | WO | disclosed |
| US-20050181117-A1 | Mixing drugs, polycaprolactone and a tetrahydrofuran solvent to form a solution, then applying the solution to a stent frame and drying the solution on the stent frame to substantially evaporate the solvent | MEDTRONIC VASCULAR, INC. (US) | 2005-08-18 | — | — | US | disclosed |
| US-20030007052-A1 | Method of preparing an inkjet ink imaged lithographic printing plate | KODAK POLYCHROME GRAPHICS, L.L.C. | 2003-01-09 | — | — | US | disclosed |
| WO-2002094571-A1 | A METHOD OF PREPARING AN INKJET INK IMAGED LITHOGRAPHIC PRINTING PLATE | KODAK POLYCHROME GRAPHICS, L.L.C. (US) | 2002-11-28 | — | — | WO | disclosed |
| EP-0428362-B1 | Photosensitive resin and element made therefrom | HOECHST CELANESE CORP (US) | 1995-04-19 | — | — | EP | disclosed |
| US-5200291-A | Photosensitive diazonium resin, element made therefrom, method of preparing the resin and method for producing negative lithographic image utilizing the resin | HOECHST CELANESE CORPORATION (US) | 1993-04-06 | — | — | US | disclosed |
| EP-0428362-A1 | Photosensitive resin and element made therefrom | HOECHST CELANESE CORPORATION (US) | 1991-05-22 | — | — | EP | disclosed |
| US-4914000-A | Three dimensional reproduction material diazonium condensates and use in light sensitive | HOECHST CELANESE CORPORATION (US) | 1990-04-03 | — | — | US | disclosed |
| EP-0326714-A2 | Three dimensional light-sensitive diazonium condensates | HOECHST CELANESE CORPORATION (US) | 1989-08-09 | — | — | EP | disclosed |
| US-4436804-A | Light-sensitive polymeric diazonium condensates and reproduction compositions and materials therewith | AMERICAN HOECHST CORPORATION (US) | 1984-03-13 | — | — | US | disclosed |
| US-4186017-A | Light-sensitive copying composition | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-29 | — | — | US | disclosed |
| US-4021243-A | Diazo light-sensitive copying composition and process of using in the manufacture of screen printing stencils | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-05-03 | — | — | US | disclosed |