Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981664 | 0.91 | GABRR1 (0.39) | MEN1GAAKMT2AGABRR1SLC7A5 | |
| SCHEMBL6981662 | 0.91 | GABRR1 (0.39) | MEN1GAAKMT2AGABRR1SLC7A5 | |
| SCHEMBL7977210 | 0.85 | MEN1 (0.35) | MEN1GAAKMT2ASLC7A5CTSL | |
| SCHEMBL7977209 | 0.85 | MEN1 (0.35) | MEN1GAAKMT2ASLC7A5CTSL | |
| SCHEMBL7762836 | 0.84 | CTSL (0.39) | MEN1GAAKMT2ASLC7A5CTSL | |
| SCHEMBL7518209 | 0.84 | CTSL (0.39) | MEN1GAAKMT2ASLC7A5CTSL | |
| SCHEMBL7518207 | 0.84 | CTSL (0.39) | MEN1GAAKMT2ASLC7A5CTSL | |
| SCHEMBL15015766 | 0.84 | CTSL (0.39) | MEN1GAAKMT2ASLC7A5CTSL | |
| SCHEMBL7838358 | 0.83 | CTSK (0.35) | MEN1GAAKMT2ASLC7A5CTSL | |
| SCHEMBL7838363 | 0.83 | CTSK (0.35) | MEN1GAAKMT2ASLC7A5CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934292-B1 | METALLOPROTEINASE INHIBITORS | VERNALIS OXFORD LTD (GB) | 2006-03-15 | — | — | EP | disclosed |
| EP-1066273-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2001-01-10 | — | — | EP | disclosed |
| US-6022873-A | Metalloproteinase inhibitors | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-02-08 | — | — | US | disclosed |
| WO-1999048881-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-09-30 | — | — | WO | disclosed |
| EP-0934292-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017655-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |