Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 8/20 | 0.47 |
| ▸ | CA9 | Q16790 | 8/20 | 0.47 |
| ▸ | CA2 | P00918 | 7/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA7 | P43166 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.38 |
| ▸ | USP8 | P40818 | 1/20 | 0.37 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9179277 | 0.74 | RET (0.53) | CA12CA9CA2CA1CA7 | |
| SCHEMBL1463156 | 0.74 | CA9 (0.50) | CA12CA9CA2CA1CA7 | |
| SCHEMBL995389 | 0.74 | CA12 (0.50) | CA12CA9CA2CA1CA7 | |
| SCHEMBL3259642 | 0.74 | CA1 (0.50) | CA12CA9CA2CA1CA7 | |
| SCHEMBL230481 | 0.74 | CA9 (0.50) | CA12CA9CA2CA1CA7 | |
| SCHEMBL193750 | 0.74 | CA12 (0.50) | CA12CA9CA2CA1CA7 | |
| SCHEMBL7288627 | 0.74 | RET (0.57) | CA12CA9CA2CA1CA7 | |
| SCHEMBL6740547 | 0.73 | CA12 (0.48) | CA12CA9CA2CA1CA7 | |
| SCHEMBL9637088 | 0.73 | CA12 (0.53) | CA12CA9CA2CA1CA7 | |
| SCHEMBL8211207 | 0.71 | CA12 (0.52) | CA12CA9CA2CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140958-B1 | ANTI-(RETRO)VIRAL CONJUGATES OF SACCHARIDES AND ACETAMIDINO OR GUANIDINO COMPOUNDS | YEDA RES & DEV (IL) | 2006-03-15 | — | — | EP | disclosed |
| US-6642365-B1 | Kanamycin, gentamycin or neomycin bonded to arginine; use for treatment of HIV infections and AIDS (acquired immune deficiency disease) | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2003-11-04 | — | — | US | disclosed |
| EP-1140958-A1 | ANTI-(RETRO)VIRAL CONJUGATES OF SACCHARIDES AND ACETAMIDINO OR GUANIDINO COMPOUNDS | YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. (IL) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039139-A1 | ANTI-(RETRO)VIRAL CONJUGATES OF SACCHARIDES AND ACETAMIDINO OR GUANIDINO COMPOUNDS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2000-07-06 | — | — | WO | disclosed |