SCHEMBL5680445

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5675941	0.91	ITGB3 (0.44)	ITGB3ITGA2BPLD2PLD1NPC1
	SCHEMBL5675889	0.88	ITGB3 (0.42)	ITGB3ITGA2BPLD2PLD1NPC1
	SCHEMBL5896610	0.87	ITGB3 (0.40)	ITGB3ITGA2BPLD2PLD1NPC1
	SCHEMBL5675927	0.84	ITGB3 (0.39)	ITGB3ITGA2BPLD2PLD1NPC1
	SCHEMBL5896585	0.84	ITGB3 (0.39)	ITGB3ITGA2BPLD2PLD1NPC1
	SCHEMBL5680056	0.83	ITGB3 (0.41)	ITGB3ITGA2BPLD2PLD1NPC1
	SCHEMBL5889465	0.81	PLD2 (0.47)	ITGB3ITGA2BPLD2PLD1NPC1
	SCHEMBL5675862	0.81	ITGB3 (0.41)	ITGB3ITGA2BMAPTPOLB
	SCHEMBL5677502	0.81	HRAS (0.37)	ITGB3ITGA2BPLD2PLD1NPC1
	SCHEMBL5889682	0.79	PLD2 (0.45)	ITGB3ITGA2BPLD2PLD1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.