Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5680920 | 1.00 | TRPA1 (0.57) | TRPA1AHRTTRALOX5PTGS1 | |
| SCHEMBL29390529 | 0.88 | TRPA1 (0.54) | TRPA1AHRTTRALOX5PTGS1 | |
| SCHEMBL41526 | 0.82 | TRPA1 (0.59) | TRPA1AHRTTRALOX5PTGS1 | |
| SCHEMBL29360472 | 0.82 | TRPA1 (0.59) | TRPA1AHRTTRALOX5PTGS1 | |
| SCHEMBL41525 | 0.82 | TRPA1 (0.59) | TRPA1AHRTTRALOX5PTGS1 | |
| SCHEMBL6722628 | 0.82 | TRPA1 (0.50) | TRPA1AHRTTRALOX5PTGS1 | |
| SCHEMBL17080305 | 0.81 | PTPN1 (0.49) | TRPA1TTRPTPN1HNF4AMEN1 | |
| Ammonia Solution, Strong SCHEMBL7940805 | 0.81 | TRPA1 (0.57) | TRPA1AHRTTRALOX5PTGS1 | |
| SCHEMBL28382096 | 0.81 | TRPA1 (0.57) | TRPA1AHRTTRALOX5PTGS1 | |
| SCHEMBL29528293 | 0.81 | TRPA1 (0.57) | TRPA1AHRTTRALOX5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7138160-B1 | Water soluble retention agent | COATEX S.A.S. (FR) | 2006-11-21 | — | — | US | claimed |
| EP-1203121-B1 | WATER SOLUBLE RETENTION AGENT | COATEX SAS (FR) | 2006-03-01 | — | — | EP | claimed |
| US-20050288428-A1 | Water soluble retention agent | COATEX S.A. (FR) | 2005-12-29 | — | — | US | claimed |
| US-20030144408-A1 | Water-retaining and optical-brightener-activating polymer composition, paper coating colors and sheets of coated paper thus obtained | COATEX S.A. (FR) | 2003-07-31 | — | — | US | claimed |
| US-6521701-B2 | Polyvinyl alcohol, water-soluble polymer at neutral or alkaline pH controlling the activation of optical brighteners, water retention and viscosities of paper coating colors | COATEX S.A.S. (FR) | 2003-02-18 | — | — | US | claimed |
| US-20020156179-A1 | Water-retaining and optical-brightener-activating polymer composition, coating slips for paper and sheets of coated paper thus obtained | COATEX S.A. (FR) | 2002-10-24 | — | — | US | claimed |
| EP-1203121-A1 | WATER SOLUBLE RETENTION AGENT | COATEX S.A.S. (FR) | 2002-05-08 | — | — | EP | claimed |
| US-20020004550-A1 | Water-retaining and optical-brightener-activating polymer composition, paper coating colors and sheets of coated paper thus obtained | COATEX S.A. (FR) | 2002-01-10 | — | — | US | claimed |
| US-6297317-B1 | POLYVINYL ALCOHOL WITH A DEGREE OF POLYMERIZATION LESS THAN 600 AND A MOLAR PERCENTAGE OF HYDROLYSIS RANGING FROM 70 TO 100% AND A WATER-SOLUBLE POLYMER AT NEUTRAL OR ALKALINE PH; CONTROLLING THE ACTIVATION OF OPTICAL BRIGHTENERS | COATEX S.A. (FR) | 2001-10-02 | — | — | US | claimed |
| WO-2001006057-A1 | WATER SOLUBLE RETENTION AGENT | COATEX S.A.S. (FR) | 2001-01-25 | — | — | WO | claimed |
| EP-1001083-A1 | Water retaining and optical brighteners activating polymeric composition, paper coating colours and coated paper | COATEX S.A. (FR) | 2000-05-17 | — | — | EP | claimed |
| US-11192991-B2 | Method for producing flame retardant polyurethane foams using halogen-free flame retardants | COVESTRO DEUTSCHLAND AG (DE) | 2021-12-07 | — | — | US | disclosed |
| US-20200140641-A1 | METHOD FOR PRODUCING FLAME RETARDANT POLYURETHANE FOAMS USING HALOGEN-FREE FLAME RETARDANTS | COVESTRO DEUTSCHLAND AG (DE) | 2020-05-07 | — | — | US | disclosed |
| US-10563032-B2 | Method for producing flame retardant polyurethane foams using halogen-free flame retardants | COVESTRO DEUTSCHLAND AG (DE) | 2020-02-18 | — | — | US | disclosed |
| EP-3221375-B1 | METHOD FOR PRODUCING FLAME-RETARDANT POLYURETHANE FOAM MATERIALS USING HALOGEN-FREE FLAME RETARDANTS | COVESTRO DEUTSCHLAND AG (DE) | 2019-06-19 | — | — | EP | disclosed |
| EP-1203121-A1 | WATER SOLUBLE RETENTION AGENT | COATEX S.A.S. (FR) | 2002-05-08 | — | — | EP | disclosed |
| US-20020004550-A1 | Water-retaining and optical-brightener-activating polymer composition, paper coating colors and sheets of coated paper thus obtained | COATEX S.A. (FR) | 2002-01-10 | — | — | US | disclosed |
| US-6297317-B1 | POLYVINYL ALCOHOL WITH A DEGREE OF POLYMERIZATION LESS THAN 600 AND A MOLAR PERCENTAGE OF HYDROLYSIS RANGING FROM 70 TO 100% AND A WATER-SOLUBLE POLYMER AT NEUTRAL OR ALKALINE PH; CONTROLLING THE ACTIVATION OF OPTICAL BRIGHTENERS | COATEX S.A. (FR) | 2001-10-02 | — | — | US | disclosed |
| WO-2001006057-A1 | WATER SOLUBLE RETENTION AGENT | COATEX S.A.S. (FR) | 2001-01-25 | — | — | WO | disclosed |
| EP-1001083-A1 | Water retaining and optical brighteners activating polymeric composition, paper coating colours and coated paper | COATEX S.A. (FR) | 2000-05-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11192991-B2 | Method for producing flame retardant polyurethane foams using halogen-free flame retardants | PFAS, PUF60, FFAR3 | TRPA1 1011/4885AHR 1911/4885TTR 979/4885 |
| US-10563032-B2 | Method for producing flame retardant polyurethane foams using halogen-free flame retardants | PFAS, PUF60, FFAR3 | TRPA1 1011/4885AHR 1911/4885TTR 979/4885 |
| US-20200140641-A1 | METHOD FOR PRODUCING FLAME RETARDANT POLYURETHANE FOAMS USING HALOGEN-FREE FLAME RETARDANTS | PFAS, PUF60, FFAR3 | TRPA1 1011/4885AHR 1911/4885TTR 979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.