Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7779507 | 1.00 | SLC22A12 (0.32) | SLC22A12GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5678034 | 0.88 | PTGDR2 (0.34) | SLC22A12HTR2AHTR2C | |
| SCHEMBL5678073 | 0.88 | NLRP3 (0.38) | SLC22A12 | |
| SCHEMBL7772318 | 0.88 | NLRP3 (0.38) | SLC22A12 | |
| SCHEMBL5678114 | 0.85 | DPP7 (0.34) | SLC22A12ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL7777106 | 0.77 | SLC22A12 (0.37) | SLC22A12MAPTHTR2AHTR2C | |
| SCHEMBL8009274 | 0.76 | KMO (0.38) | GAAALDH1A1KDM4EMAPTRCE1 | |
| SCHEMBL1981727 | 0.74 | SLC6A4 (0.34) | SLC22A12HTR2AHTR2CHTR2B | |
| SCHEMBL5678098 | 0.72 | DYRK1A (0.38) | GAASMN1; SMN2ALDH1A1KDM4EHTR2A | |
| Fumaric Acid SCHEMBL5682025 | 0.72 | SLC22A12 (0.45) | SLC22A12ALDH1A1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129078-B1 | INDAZOLE DERIVATIVES WITH 5-HT2 RECEPTOR ACTIVITY | VERNALIS RES LTD (GB) | 2006-03-15 | — | — | EP | disclosed |
| US-6552062-B1 | For therapy of central nervous system disorders; damage to the central nervous system; cardiovascular disorders; gastrointestinal disorders; diabetes insipidus, and sleep apnea, and obesity | VERNALIS RESEARCH LIMITED (GB) | 2003-04-22 | — | — | US | disclosed |