SCHEMBL5682272

SCHEMBL5682272

C=CCCC(C#N)CCC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.42
ABCC4 O15439 1/20 0.42
CYP2D6 P10635 2/20 0.41
NFKB1 P19838 2/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
BLM P54132 1/20 0.41
SLC6A3 Q01959 1/20 0.41
MEN1 O00255 1/20 0.41
TSHR P16473 1/20 0.41
CYP2C19 P33261 1/20 0.41
KMT2A Q03164 1/20 0.41
TET2 Q6N021 3/20 0.33
KDM4A O75164 2/20 0.33
KDM4C Q9H3R0 2/20 0.33
KDM2A Q9Y2K7 2/20 0.33
TET3 O43151 1/20 0.33
LMNA P02545 1/20 0.33
FOLH1 Q04609 3/20 0.32
CYP1A2 P05177 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29069484 0.84 TET2 (0.44) MAPTCYP2D6NFKB1SLC6A2SLC6A4
SCHEMBL7002068 0.83 CYP2D6 (0.42) MAPTABCC4CYP2D6NFKB1SLC6A2
Nitrous Acid SCHEMBL29026025 0.76 TET2 (0.38) MAPTCYP2D6NFKB1SLC6A2SLC6A4
SCHEMBL29239964 0.75 HDAC1 (0.42) SLC6A3MEN1TSHRKMT2ATET2
SCHEMBL29239965 0.75 HDAC1 (0.42) SLC6A3MEN1TSHRKMT2ATET2
SCHEMBL5677966 0.74 ABCC4 (0.47) MAPTABCC4CYP2D6NFKB1SLC6A2
SCHEMBL5682227 0.74 MAPT (0.42) MAPTABCC4LMNAALDH1A1
SCHEMBL29011276 0.74 FOLH1 (0.46) MAPTCYP2D6NFKB1TET2KDM4A
SCHEMBL29011277 0.74 FOLH1 (0.46) MAPTCYP2D6NFKB1TET2KDM4A
SCHEMBL6356171 0.72 GABRP (0.41) MAPTCYP2D6NFKB1TSHRTET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1335904-B1 PRODUCTION OF ALKYL 6-AMINOCAPROATE INVISTA TECH SARL (US) 2006-03-08 EP disclosed
EP-1335904-A2 PRODUCTION OF ALKYL 6-AMINOCAPROATE INVISTA Technologies S.à.r.l. (US) 2003-08-20 EP disclosed
WO-2002040452-A2 PRODUCTION OF ALKYL 6-AMINOCAPROATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2002-05-23 WO disclosed
US-6365770-B1 HYDROFORMYLATION OF 3-PENTENENITRILE TO PRODUCE 3-,4-,OR 5-FORMYLVALERONITRILE, OXIDATIVE ESTERIFICAITON TO 3-, 4-, OR 5-CYANOVALERATE, ISOLATION OF THE 5-ISOMER FOLLOWED BY HYDROGENATING E. I. DU PONT DE NEMOURS AND COMPANY 2002-04-02 US disclosed