Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5686136 | 0.85 | HSD17B10 (0.43) | KDM4EHSD17B10ALDH1A1POLBCYP2C19 | |
| SCHEMBL5682959 | 0.81 | KDM4E (0.47) | KDM4EHSD17B10ALDH1A1POLBCYP2C19 | |
| SCHEMBL8887655 | 0.81 | KDM4E (0.42) | KDM4EHSD17B10ALDH1A1POLBCYP2C19 | |
| SCHEMBL7596917 | 0.80 | KDM4E (0.46) | KDM4EHSD17B10ALDH1A1POLBCYP2C19 | |
| SCHEMBL21722984 | 0.80 | KDM4E (0.54) | KDM4EHSD17B10ALDH1A1POLBCYP2C19 | |
| SCHEMBL4973094 | 0.77 | GABRP (0.39) | KDM4EHSD17B10ALDH1A1CYP2C19RXFP1 | |
| SCHEMBL294836 | 0.76 | CYP1A2 (0.50) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7593462 | 0.75 | KMT2A (0.50) | KDM4EHSD17B10ALDH1A1POLBMEN1 | |
| SCHEMBL10739653 | 0.72 | KDM4E (0.42) | KDM4EHSD17B10ALDH1A1POLBCYP2C19 | |
| SCHEMBL7598674 | 0.72 | KMT2A (0.47) | KDM4EHSD17B10ALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1645556-A1 | Arylpiperazine-benzoylamide derivatives useful as pharmaceutical agents | Boehringer Ingelheim International GmbH (DE) | 2006-04-12 | — | — | EP | disclosed |