Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.65 |
| ▸ | PGR | P06401 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | SHBG | P04278 | 3/20 | 0.65 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.65 |
| ▸ | AR | P10275 | 2/20 | 0.61 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.61 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.58 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7596049 | 1.00 | CYP3A4 (0.65) | CYP3A4ABCB11PGRLMNASHBG | |
| SCHEMBL5686321 | 0.89 | CYP3A4 (0.65) | CYP3A4ABCB11PGRLMNASHBG | |
| Normethandrone SCHEMBL23801610 | 0.83 | PGR (0.73) | CYP3A4ABCB11PGRLMNASHBG | |
| Normethandrone SCHEMBL148631 | 0.83 | PGR (0.73) | CYP3A4ABCB11PGRLMNASHBG | |
| Normethandrone SCHEMBL148632 | 0.83 | PGR (0.73) | CYP3A4ABCB11PGRLMNASHBG | |
| SCHEMBL24476256 | 0.81 | CYP3A4 (0.70) | CYP3A4ABCB11PGRLMNASHBG | |
| SCHEMBL5683857 | 0.81 | CYP3A4 (0.69) | CYP3A4ABCB11PGRLMNASHBG | |
| Gestonorone SCHEMBL17831152 | 0.80 | CYP3A4 (0.67) | CYP3A4ABCB11PGRLMNASHBG | |
| Norethandrolone SCHEMBL23801611 | 0.80 | LMNA (0.71) | CYP3A4ABCB11PGRLMNASHBG | |
| Gestonorone SCHEMBL20488186 | 0.80 | CYP3A4 (0.67) | CYP3A4ABCB11PGRLMNASHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423407-B1 | 4-HALOGENATED 17-METHYLENE STEROIDS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | SCHERING AG (DE) | 2006-03-08 | — | — | EP | disclosed |
| US-6855836-B2 | 17-Methylene steroids, process for their production and pharmaceutical compositions that contain these compounds | JENAPHARM GMBH & CO. KG (DE) | 2005-02-15 | — | — | US | disclosed |
| WO-2002019971-A9 | 4-HALOGENATED 17-METHYLENE STEROIDS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | JENAPHARM GMBH (DE) | 2002-08-08 | — | — | WO | disclosed |