Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5681002 | 0.89 | DRD3 (0.55) | DRD3MEN1KMT2AGAARAD52 | |
| SCHEMBL6665776 | 0.86 | DRD3 (0.42) | DRD3MEN1KMT2AGAARAD52 | |
| SCHEMBL5679330 | 0.79 | DRD3 (0.51) | DRD3MEN1KMT2AGAARAD52 | |
| SCHEMBL5681491 | 0.78 | ALDH1A1 (0.58) | DRD3MEN1KMT2AGAARAD52 | |
| SCHEMBL5683667 | 0.76 | KDM4E (0.56) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL7824016 | 0.75 | DRD3 (0.63) | DRD3MEN1KMT2AGAARAD52 | |
| SCHEMBL10862874 | 0.75 | POLB (0.48) | DRD3MEN1KMT2AGAAKDM4E | |
| SCHEMBL11391209 | 0.74 | DRD3 (0.62) | DRD3MEN1KMT2AGAARAD52 | |
| SCHEMBL6669354 | 0.74 | DRD3 (0.55) | DRD3MEN1KMT2AGAARAD52 | |
| SCHEMBL11027094 | 0.74 | DRD3 (0.64) | DRD3MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831869-B1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS IN (US) | 2006-02-08 | — | — | EP | claimed |