Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 9/20 | 0.50 |
| ▸ | RAB9A | P51151 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12706012 | 0.86 | KDM4E (0.72) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL11263116 | 0.80 | KDM4E (0.71) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL11276494 | 0.78 | KDM4E (0.63) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL11263845 | 0.77 | KDM4E (0.66) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL8428113 | 0.75 | MAPT (0.41) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL29669640 | 0.74 | KDM4E (0.70) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL11269773 | 0.74 | KDM4E (0.69) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL28759994 | 0.74 | KDM4E (0.70) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL11269758 | 0.74 | KDM4E (0.69) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL12706190 | 0.74 | KDM4E (0.64) | KDM4EPOLBNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321396-A | Copolymerizable, ultraviolet light absorber allyloxy-2-(2H-benzotriazol-2-yl)-4-alkylbenzenes | GAF CORPORATION (US) | 1982-03-23 | — | — | US | claimed |
| EP-1096905-B1 | UV BLOCKING LENSES AND MATERIAL CONTAINING BENZOTRIAZOLES AND BENZOPHENONES | NOVARTIS AG (CH) | 2006-02-08 | — | — | EP | disclosed |
| US-6244707-B1 | CONTACT LENSES, INTRAOCULAR LENSES, AND TRANSPARENT PLASTIC WITH ENHANCED ULTRAVIOLET BLOCKING INCLUDES A HYDROGEL POLYMER OF TWO ABSORBERS (A BENZOTRIAZOLE DERIVATIVE AND BENZOPHENONE DERIVATIVE) | WESLEY JESSEN CORPORATION | 2001-06-12 | — | — | US | disclosed |