Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 2/20 | 0.45 |
| ▸ | FABP6 | P51161 | 1/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.45 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.45 |
| ▸ | MASP2 | O00187 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2163036 | 0.87 | TYMS (0.52) | ALDH1A1NPC1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL5679580 | 0.87 | MAP4K4 (0.49) | ALDH1A1NPC1PKMSMN1; SMN2RAB9A | |
| Bromide SCHEMBL17747821 | 0.85 | TYMS (0.51) | ALDH1A1NPC1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL4323448 | 0.83 | NPC1 (0.49) | ALDH1A1NPC1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL5679426 | 0.82 | FABP6 (0.53) | ALDH1A1NPC1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL419326 | 0.81 | NPC1 (0.71) | ALDH1A1NPC1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL5680087 | 0.81 | TYMS (0.44) | ALDH1A1NPC1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL3827667 | 0.80 | ALDH1A1 (0.58) | ALDH1A1NPC1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL14395105 | 0.80 | LOXL2 (0.57) | FABP6MAPT | |
| Hydrochloric Acid SCHEMBL7240756 | 0.79 | CCR1 (0.47) | ALDH1A1NPC1PKMSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620413-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004098494-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2004-11-18 | — | — | WO | disclosed |