Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 4/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 1/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5684293 | 1.00 | TSHR (0.44) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL5684072 | 0.99 | TSHR (0.42) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL5684491 | 0.95 | KCNJ1 (0.38) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL5683617 | 0.91 | KCNJ1 (0.39) | HSD17B10RARBRARARARGKCNJ1 | |
| SCHEMBL5684048 | 0.89 | RARB (0.40) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL5685170 | 0.89 | RARB (0.40) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL5683403 | 0.89 | KCNJ1 (0.47) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL5684738 | 0.89 | KCNJ1 (0.47) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL5684136 | 0.88 | RARB (0.38) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL5687512 | 0.87 | KCNJ1 (0.48) | TSHRHSD17B10RARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067179-B1 | Fused ring compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1201632-B1 | FUSED RING COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2006-03-29 | — | — | EP | disclosed |
| EP-1201632-A1 | FUSED RING COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-02 | — | — | EP | disclosed |