Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | IL2 | P60568 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330422 | 0.84 | ATM (0.48) | HTTLMNAMAPTKDM4EATM | |
| SCHEMBL257654 | 0.83 | KDM4E (0.45) | HTTLMNAMAPTKDM4EATM | |
| SCHEMBL10895787 | 0.82 | KDM4E (0.44) | HTTLMNAMAPTKDM4EATM | |
| SCHEMBL5549386 | 0.79 | KDM4E (0.42) | HTTLMNAMAPTKDM4E | |
| SCHEMBL668833 | 0.79 | HTT (0.43) | HTTLMNAMAPTKDM4EATM | |
| SCHEMBL8622918 | 0.79 | HTT (0.47) | HTTLMNAMAPTKDM4EATM | |
| SCHEMBL9054634 | 0.79 | KDM4E (0.44) | HTTLMNAMAPTKDM4EATM | |
| SCHEMBL499545 | 0.79 | ATM (0.46) | HTTLMNAMAPTKDM4EATM | |
| SCHEMBL8815409 | 0.78 | KDM4E (0.41) | HTTLMNAMAPTKDM4EATM | |
| SCHEMBL31048531 | 0.78 | KDM4E (0.53) | HTTLMNAMAPTKDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067179-B1 | Fused ring compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1201632-B1 | FUSED RING COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2006-03-29 | — | — | EP | disclosed |
| EP-1201632-A1 | FUSED RING COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-02 | — | — | EP | disclosed |