Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10895787 | 0.88 | KDM4E (0.44) | KDM4EHTTATMALDH1A1HPGD | |
| SCHEMBL257654 | 0.80 | KDM4E (0.45) | KDM4EHTTATMALDH1A1HPGD | |
| SCHEMBL1272427 | 0.79 | POLB (0.44) | KDM4EHTTALDH1A1MAPTLMNA | |
| SCHEMBL5684165 | 0.79 | HTT (0.45) | KDM4EHTTATMALDH1A1HPGD | |
| SCHEMBL9842227 | 0.78 | ATM (0.56) | KDM4EHTTATMALDH1A1HPGD | |
| SCHEMBL5549386 | 0.77 | KDM4E (0.42) | KDM4EHTTMAPTLMNASMN1; SMN2 | |
| SCHEMBL11085738 | 0.76 | KDM4E (0.42) | KDM4EHTTATMALDH1A1HPGD | |
| SCHEMBL655887 | 0.76 | HPGD (0.46) | KDM4EHTTATMALDH1A1HPGD | |
| SCHEMBL1276310 | 0.76 | KDM4E (0.51) | KDM4EHTTATMALDH1A1HPGD | |
| SCHEMBL8815409 | 0.75 | KDM4E (0.41) | KDM4EHTTATMALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4389733-A1 | METHOD FOR PREPARING 5-BROMO-2-CHLORO-BENZOIC ACID AS RAW MATERIAL IN HYPOGLYCEMIC DRUG SYNTHESIS | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2024-06-26 | — | — | EP | disclosed |
| WO-1996014302-A1 | PYRAZOLE DERIVATIVES EXHIBITING ANTI-INFLAMMATORY AND ANALGESIC EFFECTS | EISAI CO., LTD. (JP) | 1996-05-17 | — | — | WO | disclosed |
| US-4501895-A | ELASTIN DEGRADATION INHIBITION | G.D. SEARLE & CO. (US) | 1985-02-26 | — | — | US | disclosed |
| EP-0126372-A1 | Halogenated protease inhibitors | G.D. Searle & Co. (US) | 1984-11-28 | — | — | EP | disclosed |
| US-4469885-A | Halogenated protease inhibitors | G. D. SEARLE & CO. (US) | 1984-09-04 | — | — | US | disclosed |