Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5252580 | 0.80 | KDM4E (0.41) | KDM4ECYP2D6HTTATMALDH1A1 | |
| SCHEMBL257654 | 0.80 | KDM4E (0.45) | KDM4ECYP2D6HTTATMALDH1A1 | |
| SCHEMBL5684165 | 0.78 | HTT (0.45) | KDM4EHTTATMALDH1A1LMNA | |
| SCHEMBL10895787 | 0.78 | KDM4E (0.44) | KDM4ECYP2D6HTTATMALDH1A1 | |
| SCHEMBL5549386 | 0.76 | KDM4E (0.42) | KDM4EHTTLMNAMAPTHRH3 | |
| SCHEMBL9054634 | 0.75 | KDM4E (0.44) | KDM4EHTTATMALDH1A1LMNA | |
| SCHEMBL9791086 | 0.74 | KDM4E (0.38) | KDM4ECYP2D6HTTATMALDH1A1 | |
| SCHEMBL6261909 | 0.74 | KDM4E (0.40) | KDM4ECYP2D6HTTATMALDH1A1 | |
| SCHEMBL7491866 | 0.74 | KDM4E (0.41) | KDM4ECYP2D6HTTATMALDH1A1 | |
| SCHEMBL10351615 | 0.74 | KDM4E (0.53) | KDM4ECYP2D6MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027187-A1 | ISOXAZOLE AND 2-CYANO-1,3-DIONES DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-31 | — | — | WO | disclosed |