Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5680344 | 0.94 | MAOB (0.49) | MAOBMAOASCN9APARP10 | |
| SCHEMBL5684098 | 0.88 | MAOB (0.53) | MAOBMAOASCN9APARP10PPARA | |
| SCHEMBL5682138 | 0.85 | ALDH1A1 (0.47) | MAOBPARP10 | |
| SCHEMBL5681627 | 0.84 | GID4 (0.52) | MAOBMAOA | |
| SCHEMBL5681586 | 0.84 | PARP15 (0.50) | MAOBMAOAPARP10 | |
| SCHEMBL5684577 | 0.81 | FFAR1 (0.49) | MAOBMAOASCN9APPARA | |
| SCHEMBL1067948 | 0.80 | MAOB (0.65) | MAOBMAOASCN9APARP10PPARA | |
| SCHEMBL5684437 | 0.80 | SCN3A (0.55) | MAOBSCN9APARP10 | |
| SCHEMBL5684554 | 0.79 | TP53 (0.41) | MAOBMAOASCN9A | |
| SCHEMBL5536874 | 0.77 | MAOB (0.53) | MAOBMAOASCN9APARP10PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044186-B9 | SUBSTITUTED 2-BENZYLAMINO-2-PHENYL-ACETAMIDE COMPOUNDS | NEWRON PHARM SPA (IT) | 2006-06-21 | — | — | EP | disclosed |
| EP-1044186-B1 | SUBSTITUTED 2-BENZYLAMINO-2-PHENYL-ACETAMIDE COMPOUNDS | NEWRON PHARM SPA (IT) | 2006-03-08 | — | — | EP | disclosed |
| US-6303819-B1 | SODIUM CHANNEL-BLOCKING AGENT; CHRONIC OR NEUROPATHIC PAIN. | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2001-10-16 | — | — | US | disclosed |