SCHEMBL5684791

SCHEMBL5684791

CNCC1CCCC(NC)C1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.35
ADH1B P00325 2/20 0.30
ADH1C P00326 2/20 0.30
ADH1A P07327 2/20 0.30
ADH7 P40394 2/20 0.30
ADH4 P08319 1/20 0.30
LRRK2 Q5S007 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19418920 1.00 SIGMAR1 (0.35) SIGMAR1ADH1BADH1CADH1AADH7
SCHEMBL18543781 0.86
SCHEMBL18543793 0.86
SCHEMBL8368333 0.84 SIGMAR1 (0.41) SIGMAR1ADH1BADH1CADH1AADH7
SCHEMBL2014927 0.82 ADH1B (0.32) ADH1BADH1CADH1AADH7LRRK2
SCHEMBL17150880 0.80 ADH1B (0.31) ADH1BADH1CADH1AADH7LRRK2
SCHEMBL18876633 0.80 ADH1B (0.31) ADH1BADH1CADH1AADH7LRRK2
SCHEMBL20048886 0.80 ADH1B (0.31) ADH1BADH1CADH1AADH7LRRK2
SCHEMBL26443047 0.80 ADH1B (0.31) ADH1BADH1CADH1AADH7LRRK2
SCHEMBL23903180 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0895984-B1 ALICYCLIC POLYAMINES AND PROCESS FOR THE PREPARATION THEREOF DAICEL CHEM (JP) 2006-04-12 EP disclosed
US-6100430-A ALICYCLIC COMPOUND CONTAINING TWO PRIMARY, SECONDARY AND/OR TERTIARY AMINO GROUPS AND HAVING A CARBON ATOM IN THE RING SUBSTITUTED WITH TWO ALKYL GROUPS; MAKING BY REDUCTIVE AMINATION OF A 3-FORMYLCYCLOALKENONE OR 3-FORMYLCYCLOALKANONE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2000-08-08 US disclosed
EP-0895984-A1 ALICYCLIC POLYAMINES AND PROCESS FOR THE PREPARATION THEREOF DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-02-10 EP disclosed