Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5684807 | 0.85 | TSHR (0.37) | ALDH1A1TDP1L3MBTL1TP53SMN1; SMN2 | |
| SCHEMBL2445733 | 0.82 | TDP1 (0.42) | ALDH1A1TDP1L3MBTL1TP53SMN1; SMN2 | |
| SCHEMBL125182 | 0.82 | TDP1 (0.42) | ALDH1A1TDP1L3MBTL1TP53SMN1; SMN2 | |
| SCHEMBL5687227 | 0.81 | MEN1 (0.39) | ALDH1A1TDP1TP53SMN1; SMN2CYP3A4 | |
| Aniline SCHEMBL16147722 | 0.77 | — | — | |
| SCHEMBL10943391 | 0.77 | TDP1 (0.37) | ALDH1A1TDP1L3MBTL1TP53SMN1; SMN2 | |
| SCHEMBL16147719 | 0.76 | TDP1 (0.36) | ALDH1A1TDP1L3MBTL1TP53SMN1; SMN2 | |
| SCHEMBL19579594 | 0.74 | TDP1 (0.35) | ALDH1A1TDP1L3MBTL1TP53SMN1; SMN2 | |
| SCHEMBL27944700 | 0.72 | APP (0.33) | TSHRMAPTMAPK1APPGAA | |
| SCHEMBL29192707 | 0.71 | NPC1 (0.33) | ALDH1A1L3MBTL1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478651-B1 | PREPARATION OF N-SUBSTITUTED AMINOORGANOSILANES | GEN ELECTRIC (US) | 2006-02-08 | — | — | EP | claimed |
| US-6448425-B1 | N-CYCLOALKYLAMINOALKYLSILANES BY HYDROGENATING N-ARYLAMINO-ALKYLSILANES; PALLADIUM, PLATINUM, NICKEL, RHENIUM, RHODIUM, RUTHENIUM, COPPER CHROMITE CATALYST; N-CYCLOHEXYL-3-AMINOPROPYLTRIMETHOXYSILANE FROM | CROMPTON CORPORATION | 2002-09-10 | — | — | US | claimed |
| EP-1478651-B1 | PREPARATION OF N-SUBSTITUTED AMINOORGANOSILANES | GEN ELECTRIC (US) | 2006-02-08 | — | — | EP | disclosed |
| EP-1478651-A1 | PREPARATION OF N-SUBSTITUTED AMINOORGANOSILANES | GENERAL ELECTRIC COMPANY (US) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003070734-A1 | PREPARATION OF N-SUBSTITUTED AMINOORGANOSILANES | GENERAL ELECTRIC COMPANY (US) | 2003-08-28 | — | — | WO | disclosed |