SCHEMBL125182

SCHEMBL125182

CCC(Nc1ccccc1)[Si](OC)(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.42
ALDH1A1 P00352 5/20 0.37
CYP3A4 P08684 3/20 0.37
ALOX15 P16050 3/20 0.37
TSHR P16473 3/20 0.37
HSD17B10 Q99714 3/20 0.37
THRB P10828 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
ALOX12 P18054 2/20 0.37
LMNA P02545 1/20 0.37
RECQL P46063 1/20 0.37
ATM Q13315 1/20 0.37
GAA P10253 2/20 0.37
HIF1A Q16665 2/20 0.36
TP53 P04637 1/20 0.36
HSP90AA1 P07900 1/20 0.36
CASP1 P29466 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MAPK1 P28482 1/20 0.36
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2445733 1.00 TDP1 (0.42) TDP1ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL10943391 0.93 TDP1 (0.37) TDP1ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL16147719 0.92 TDP1 (0.36) TDP1ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL19579594 0.91 TDP1 (0.35) TDP1ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL2117717 0.86 TDP1 (0.39) TDP1ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL3450824 0.84 TDP1 (0.41) TDP1ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL138740 0.84 TDP1 (0.41) TDP1ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL9069335 0.82 TDP1 (0.39) TDP1ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL5685206 0.82 ALDH1A1 (0.38) TDP1ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL27944700 0.82 APP (0.33) TSHRGAAMAPK1MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3615 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630697-B2 Polyaminosiloxane water tree repellant for electrical insulation DOW GLOBAL TECHNOLOGIES LLC (US) 2026-05-19 US claimed
US-20260071104-A1 Anionic Curable Compositions DESIGNER MOLECULES INC (US) 2026-03-12 US claimed
US-12522741-B2 Infrared permeable ink composition, optical filter formed thereby, and electronic apparatus including the optical filter SAMSUNG DISPLAY CO., LTD. (KR) 2026-01-13 US claimed
EP-4638540-A1 A METHOD FOR PREPARING A SILANISED POLYURETHANE PREPOLYMER, ITS USE AND A METHOD FOR PRODUCING A MOISTURE-CURED SILANISED ONE-COMPONENT FOAM PCC ROKITA Spolka Akcyjna (PL) 2025-10-29 EP claimed
US-20250326910-A1 METHOD FOR PRODUCING SURFACE-MODIFIED MICRO-FIBRILLATED CELLULOSE DÄTWYLER SCHWEIZ AG (CH) 2025-10-23 US claimed
EP-4636126-A1 SURFACE TREATMENT SOLUTION COMPOSITION FOR PLATED STEEL SHEET, PLATED STEEL SHEET SURFACE-TREATED USING SAME AND METHOD FOR MANUFACTURING THEREOF POSCO Co., Ltd (KR) 2025-10-22 EP claimed
CN-119819360-A Preparation method of hierarchical titanium-silicon molecular sieve containing framework manganese and application of hierarchical titanium-silicon molecular sieve in preparation of adipic acid 四川大学 2025-04-15 CN claimed
EP-4532567-A1 METHOD FOR PRODUCING SURFACE-MODIFIED MICRO-FIBRILLATED CELLULOSE Dätwyler Schweiz AG (CH) 2025-04-09 EP claimed
CN-119751928-A Infrared blocking master batch and preparation method and application thereof 中国科学院赣江创新研究院 2025-04-04 CN claimed
WO-2025071053-A1 RESIN COMPOSITION FOR USE AS MOLDING MATERIAL 주식회사 케이씨씨 2025-04-03 WO claimed
EP-0320861-A2 Oxidation resistant compositions for use with rare earth magnets THE B.F. GOODRICH COMPANY (US) 1989-06-21 EP claimed
US-4758624-A Silane-crosslinkable halogenated polymer composition and process of crosslinking the same FUJIKURA LTD. (JP) 1988-07-19 US claimed
US-4729771-A POLYIMIDE MATRIX, ABRASIVE PARTICLES UBE INDUSTRIES, LTD. (JP) 1988-03-08 US claimed
EP-0107636-B1 MULTICOMPONENT MEMBRANE FOR GAS SEPARATION Monsanto Company (US) 1986-12-30 EP claimed
EP-0171986-A1 Silane-crosslinkable halogenated polymer composition and process of crosslinking the same FUJIKURA LTD. (JP) 1986-02-19 EP claimed
EP-0107636-A1 Multicomponent membrane for gas separation Monsanto Company (US) 1984-05-02 EP claimed
US-4414272-A SILICA, EPOXIDE, SILANE COUPLER OR ORGANOTITANIUM COMPOUND TEIJIN LIMITED (JP) 1983-11-08 US claimed
EP-0048481-A2 Shaped polyester composite material having an activated surface thereof and process for producing the same TEIJIN LIMITED (JP) 1982-03-31 EP claimed
US-4062999-A Synthetic organic fibers coated with an amino silane and an epoxy siloxane containing treating agent TEIJIN LIMITED (JA) 1977-12-13 US claimed
US-3980599-A FILLINGS FOR QUILTS TEIJIN LIMITED (JA) 1976-09-14 US claimed