Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | LSS | P48449 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5684932 | 0.86 | CYP2C9 (0.35) | DRD2CYP2C9DRD3CYP3A4CYP2C8 | |
| SCHEMBL5687177 | 0.84 | S1PR1 (0.36) | DRD2SRD5A1LSSL3MBTL1MCHR1 | |
| SCHEMBL5687195 | 0.84 | S1PR1 (0.36) | DRD2SRD5A1LSSL3MBTL1MCHR1 | |
| SCHEMBL5687178 | 0.84 | S1PR1 (0.36) | DRD2SRD5A1LSSL3MBTL1MCHR1 | |
| SCHEMBL5687190 | 0.84 | S1PR1 (0.36) | DRD2SRD5A1LSSL3MBTL1MCHR1 | |
| SCHEMBL5686400 | 0.83 | SGPL1 (0.34) | DRD2SRD5A1LSSL3MBTL1 | |
| SCHEMBL5684380 | 0.83 | DRD2 (0.39) | DRD2CYP2C9DRD3CYP3A4CYP2C8 | |
| SCHEMBL5686403 | 0.83 | SGPL1 (0.34) | DRD2SRD5A1LSSL3MBTL1 | |
| SCHEMBL5687262 | 0.83 | HTR1D (0.38) | DRD2DRD3CYP3A4CYP2C8S1PR3 | |
| SCHEMBL5683979 | 0.83 | MEN1 (0.34) | DRD2CYP2C9DRD3CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067179-B1 | Fused ring compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1201632-B1 | FUSED RING COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2006-03-29 | — | — | EP | disclosed |
| EP-1201632-A1 | FUSED RING COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-02 | — | — | EP | disclosed |