Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5686449 | 0.93 | CYP3A4 (0.38) | HRH3MCHR1CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL5684665 | 0.92 | CYP3A4 (0.41) | HRH3CYP2C9CYP3A4CYP2C8S1PR3 | |
| SCHEMBL5687544 | 0.91 | CYP3A4 (0.43) | HRH3CYP2C9CYP3A4CYP2C8S1PR3 | |
| SCHEMBL5687345 | 0.91 | CYP3A4 (0.43) | HRH3CYP2C9CYP3A4CYP2C8S1PR3 | |
| SCHEMBL5684524 | 0.90 | MCHR1 (0.34) | HRH3MCHR1CYP19A1DRD2DRD3 | |
| SCHEMBL14526393 | 0.84 | MEN1 (0.37) | MEN1MAPK1KMT2AHRH3ALDH1A1 | |
| SCHEMBL5684932 | 0.83 | CYP2C9 (0.35) | MEN1MAPK1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL5685243 | 0.83 | DRD2 (0.44) | MEN1MAPK1KMT2AALDH1A1MCHR1 | |
| SCHEMBL5684693 | 0.82 | CYP3A4 (0.34) | ALDH1A1CYP3A4CYP2C8S1PR3DRD2 | |
| SCHEMBL5684380 | 0.80 | DRD2 (0.39) | MEN1MAPK1KMT2AALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067179-B1 | Fused ring compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1201632-B1 | FUSED RING COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2006-03-29 | — | — | EP | disclosed |
| EP-1201632-A1 | FUSED RING COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-02 | — | — | EP | disclosed |