Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6097220 | 0.81 | MAOB (0.53) | MAOBCNR2CNR1NPC1RAB9A | |
| SCHEMBL13034049 | 0.73 | ALDH1A1 (0.54) | MAOBNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL6894576 | 0.71 | GAA (0.51) | POLBALDH1A1KMT2AGLAMEN1 | |
| SCHEMBL1303551 | 0.70 | NPC1 (0.68) | MAOBNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL5685093 | 0.69 | ALDH1A1 (0.40) | POLBSMN1; SMN2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL2636206 | 0.68 | HTT (0.49) | CNR2CNR1NPC1RAB9APOLB | |
| SCHEMBL25424107 | 0.68 | HTR1A (0.45) | MAOBCNR2CNR1ALDH1A1MAPT | |
| SCHEMBL7822285 | 0.68 | ALDH1A1 (0.39) | POLBSMN1; SMN2ALDH1A1KMT2AHTT | |
| SCHEMBL9732613 | 0.68 | MAOB (0.58) | MAOBNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL12968393 | 0.68 | MAOB (0.58) | MAOBNPC1RAB9APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210327-B1 | NEW VITAMIN D DERIVATIVES WITH CYCLIC SUBSTRUCTURES IN THE SIDE CHAINS, METHOD AND INTERMEDIATES FOR THEIR PRODUCTION AND THEIR USE IN THE PREPARATION OF MEDICAMENTS | SCHERING AG (DE) | 2006-01-18 | — | — | EP | disclosed |
| EP-1362848-A1 | Process for the preparation of vitamin D derivatives | Schering Aktiengesellschaft (DE) | 2003-11-19 | — | — | EP | disclosed |