Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24391135 | 0.83 | PDE3B (0.46) | TSHRCASP1MKNK1MKNK2MAP4K4 | |
| SCHEMBL529645 | 0.81 | ALDH1A1 (0.50) | NPC1RAB9ATSHRCASP1MKNK1 | |
| SCHEMBL7089197 | 0.81 | MAP4K4 (0.42) | NPC1RAB9ATSHRCASP1MKNK1 | |
| SCHEMBL4446669 | 0.80 | MKNK1 (0.46) | TSHRMKNK1MKNK2KDM4EALDH1A1 | |
| SCHEMBL5684565 | 0.79 | NPC1 (0.49) | NPC1RAB9ATSHRCASP1MAP4K4 | |
| SCHEMBL5685526 | 0.79 | NPC1 (0.49) | NPC1RAB9ATSHRCASP1MAP4K4 | |
| SCHEMBL5688111 | 0.78 | TSHR (0.48) | NPC1RAB9ATSHRCASP1PDE10A | |
| Hydrochloric Acid SCHEMBL5685128 | 0.77 | TSHR (0.47) | NPC1RAB9ATSHRCASP1PDE10A | |
| SCHEMBL31469002 | 0.77 | MKNK1 (0.52) | NPC1TSHRMKNK1MKNK2PDE10A | |
| SCHEMBL3421959 | 0.77 | MKNK1 (0.52) | NPC1TSHRMKNK1MKNK2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7077872-B2 | Oxidation hair dyes containing 3-aminophenol derivatives, and novel 3-aminophenol derivatives | WELLA AG (DE) | 2006-07-18 | — | — | US | disclosed |
| EP-1418879-B1 | OXIDATION HAIR DYES CONTAINING 3-AMINOPHENOL DERIVATIVES, AND NOVEL 3-AMINOPHENOL DERIVATIVES | WELLA AG (DE) | 2006-04-12 | — | — | EP | disclosed |
| US-20040200010-A1 | Oxidation hair dyes containing 3-aminophenol derivatives, and novel 3-aminophenol derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2004-10-14 | — | — | US | disclosed |
| EP-1418879-A1 | OXIDATION HAIR DYES CONTAINING 3-AMINOPHENOL DERIVATIVES, AND NOVEL 3-AMINOPHENOL DERIVATIVES | Wella Aktiengesellschaft (DE) | 2004-05-19 | — | — | EP | disclosed |
| WO-2003017955-A1 | OXIDATION HAIR DYES CONTAINING 3-AMINOPHENOL DERIVATIVES, AND NOVEL 3-AMINOPHENOL DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2003-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040200010-A1 | Oxidation hair dyes containing 3-aminophenol derivatives, and novel 3-aminophenol derivatives | KRT18, S100P, ALDH7A1 | NPC1 4810/4885RAB9A 4733/4885TSHR 2675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.