Tetraethylene Glycol

Tetraethylene Glycol

SCHEMBL5685609

C=CC(=O)OC.CCOCC.OCCOCCOCCOCCO

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 10/20 0.47
ALDH1A1 P00352 7/20 0.47
TP53 P04637 3/20 0.47
HIF1A Q16665 3/20 0.47
HSD17B10 Q99714 1/20 0.47
THRB P10828 3/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 2/20 0.36
CYP3A4 P08684 2/20 0.34
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
EPHX2 P34913 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triethylene Glycol SCHEMBL3127486 1.00 TSHR (0.47) TSHRALDH1A1TP53HIF1AHSD17B10
Di(Hydroxyethyl)Ether SCHEMBL1174196 0.98 TSHR (0.48) TSHRALDH1A1TP53HIF1AHSD17B10
Diethylene Glycol Monoethyl Ether SCHEMBL27698223 0.96 ALDH1A1 (0.50) TSHRALDH1A1TP53HIF1AHSD17B10
Acrylic Acid Methyl Ester SCHEMBL27698226 0.96 ALDH1A1 (0.50) TSHRALDH1A1TP53HIF1AHSD17B10
Acrylic Acid Methyl Ester SCHEMBL910221 0.93 ALDH1A1 (0.54) TSHRALDH1A1TP53HIF1AHSD17B10
Triethylene Glycol SCHEMBL3176732 0.93 TSHR (0.54) TSHRALDH1A1TP53HIF1AHSD17B10
Tetraethylene Glycol SCHEMBL27499881 0.93 TSHR (0.54) TSHRALDH1A1TP53HIF1AHSD17B10
Di(Hydroxyethyl)Ether SCHEMBL11856454 0.91 TSHR (0.56) TSHRALDH1A1TP53HIF1AHSD17B10
Acrylic Acid Methyl Ester SCHEMBL22263205 0.89 TSHR (0.43) TSHRALDH1A1TP53HIF1AHSD17B10
Acrylic Acid Methyl Ester SCHEMBL28771788 0.87 TSHR (0.48) TSHRALDH1A1TP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9513406-B2 Soluble functionalized nanoparticles for use in optical materials UNIVERSITY OF OREGON (US) 2016-12-06 US claimed
US-20150021528-A1 SOLUBLE FUNCTIONALIZED NANOPARTICLES FOR USE IN OPTICAL MATERIALS STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF UNIVERSITY (US) 2015-01-22 US claimed
US-20250360491-A1 STATIONARY PHASE FOR CHROMATOGRAPHY DAICEL CORPORATION (JP) 2025-11-27 US disclosed
US-12403452-B2 Stationary phase for chromatography DAICEL CORPORATION (JP) 2025-09-02 US disclosed
CN-119425650-A Stationary phase for chromatography 株式会社大赛璐 2025-02-14 CN disclosed
EP-3904408-B1 SOFT INTRAOCULAR LENS MATERIAL AND SOFT INTRAOCULAR LENS NIDEK KK (JP) 2024-11-20 EP disclosed
CN-115975105-B Soft intraocular lens material and soft intraocular lens 株式会社尼德克 2024-11-19 CN disclosed
CN-112638519-B stationary phase for chromatography 株式会社大赛璐 2023-11-10 CN disclosed
CN-115975105-A Soft intraocular lens material and soft intraocular lens 株式会社尼德克 2023-04-18 CN disclosed
CN-113195563-B Soft intraocular lens material and soft intraocular lens 株式会社尼德克 2022-12-23 CN disclosed
EP-3904408-A1 SOFT INTRAOCULAR LENS MATERIAL AND SOFT INTRAOCULAR LENS Nidek Co., Ltd. (JP) 2021-11-03 EP disclosed
CN-112638519-A Stationary phase for chromatography 株式会社大赛璐 2021-04-09 CN disclosed
WO-2020138346-A1 SOFT INTRAOCULAR LENS MATERIAL AND SOFT INTRAOCULAR LENS 株式会社ニデック 2020-07-02 WO disclosed
WO-2020045648-A1 STATIONARY PHASE FOR CHROMATOGRAPHY 株式会社ダイセル 2020-03-05 WO disclosed
US-9513406-B2 Soluble functionalized nanoparticles for use in optical materials UNIVERSITY OF OREGON (US) 2016-12-06 US disclosed
US-20150021528-A1 SOLUBLE FUNCTIONALIZED NANOPARTICLES FOR USE IN OPTICAL MATERIALS STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF UNIVERSITY (US) 2015-01-22 US disclosed
US-20150023643-A1 GRADIENT OPTICAL POLYMER NANOCOMPOSITES State of Oregon acting by and through the State Board of Higher Education on behalf of the Univers (US) 2015-01-22 US disclosed
EP-1354898-B1 MONOMER COMPOSITION, POLYMER OBTAINED THEREFROM, AND OCULAR LENS JOHNSON & JOHNSON VISION CARE (US) 2006-04-26 EP disclosed
US-20060012750-A1 Monomer composition and polysmers and ophthalmic lenses in which it is used JOHNSON & JOHNSON VISION CARE, INC. 2006-01-19 US disclosed
EP-1354898-A1 MONOMER COMPOSITION, POLYMER OBTAINED THEREFROM, AND OCULAR LENS Johnson & Johnson Vision Care, Inc. (US) 2003-10-22 EP disclosed