Acrylic Acid Methyl Ester

Acrylic Acid Methyl Ester

SCHEMBL910221

C=CC(=O)OC.CCOCCO

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.54
TSHR P16473 11/20 0.50
HPGD P15428 1/20 0.41
TP53 P04637 3/20 0.41
HIF1A Q16665 3/20 0.41
HSD17B10 Q99714 1/20 0.41
THRB P10828 3/20 0.39
CYP3A4 P08684 2/20 0.36
KEAP1 Q14145 1/20 0.34
NFE2L2 Q16236 1/20 0.34
HCAR2 Q8TDS4 1/20 0.34
MAPK1 P28482 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Methyl Ester SCHEMBL27698226 0.96 ALDH1A1 (0.50) ALDH1A1TSHRHPGDTP53HIF1A
Diethylene Glycol Monoethyl Ether SCHEMBL27698223 0.96 ALDH1A1 (0.50) ALDH1A1TSHRHPGDTP53HIF1A
Di(Hydroxyethyl)Ether SCHEMBL1174196 0.94 TSHR (0.48) ALDH1A1TSHRHPGDTP53HIF1A
Tetraethylene Glycol SCHEMBL5685609 0.93 TSHR (0.47) ALDH1A1TSHRHPGDTP53HIF1A
Triethylene Glycol SCHEMBL3127486 0.93 TSHR (0.47) ALDH1A1TSHRHPGDTP53HIF1A
Di(Hydroxyethyl)Ether SCHEMBL11856454 0.90 TSHR (0.56) ALDH1A1TSHRHPGDTP53HIF1A
Acrylic Acid Methyl Ester SCHEMBL28310777 0.90 TSHR (0.50) ALDH1A1TSHRHPGDTP53HIF1A
Tetraethylene Glycol SCHEMBL27499881 0.88 TSHR (0.54) ALDH1A1TSHRHPGDTP53HIF1A
Triethylene Glycol SCHEMBL3176732 0.88 TSHR (0.54) ALDH1A1TSHRHPGDTP53HIF1A
Acrylic Acid Methyl Ester SCHEMBL22263205 0.88 TSHR (0.43) ALDH1A1TSHRHPGDTP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104861109-B Film-forming resin with water solubility and oil solubility as well as preparation method and application thereof 中国科学院理化技术研究所 2017-06-13 CN claimed
US-8282872-B2 (Meth)acrylate compound, curable composition using the same, curable composition for photo-nanoimprints, cured product of curable composition and method for manufacturing cured product FUJIFILM CORPORATION (JP) 2012-10-09 US disclosed
US-20110003909-A1 (METH)ACRYLATE COMPOUND, CURABLE COMPOSITION USING THE SAME, CURABLE COMPOSITION FOR PHOTO-NANOIMPRINTS, CURED PRODUCT OF CURABLE COMPOSITION AND METHOD FOR MANUFACTURING CURED PRODUCT FUJIFILM CORPORATION 2011-01-06 US disclosed
CN-1082679-C Photosensitive resin composition for sandblast resist MATSUSHITA ELECTRIC CORP (JP) 2002-04-10 CN disclosed
CN-1140843-A Photosensitive resin composition for sandblast resist MATSUSHITA ELECTRIC CORP (JP) 1997-01-22 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110003909-A1 (METH)ACRYLATE COMPOUND, CURABLE COMPOSITION USING THE SAME, CURABLE COMPOSITION FOR PHOTO-NANOIMPRINTS, CURED PRODUCT OF CURABLE COMPOSITION AND METHOD FOR MANUFACTURING CURED PRODUCT DNMT3A, DOT1L, PDE6D ALDH1A1 195/4885TSHR 2573/4885HPGD 2471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.