SCHEMBL5685995

SCHEMBL5685995

CCC#Cc1ccccc1C(ON(CC)CC)(C(=O)O)C1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 7/20 0.42
CHRM1 P11229 7/20 0.42
CHRM4 P08173 5/20 0.42
CHRM3 P20309 5/20 0.42
KCNH2 Q12809 3/20 0.42
CYP2C19 P33261 2/20 0.42
CYP2D6 P10635 2/20 0.42
SLC6A3 Q01959 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
PKM P14618 1/20 0.42
NFKB1 P19838 1/20 0.42
THPO P40225 1/20 0.42
ABCB11 O95342 1/20 0.42
ESR1 P03372 1/20 0.42
CHRM5 P08912 1/20 0.42
ADRA2A P08913 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
TBXA2R P21731 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5699167 0.99 MEN1 (0.43) CHRM2CHRM1CHRM4CHRM3KCNH2
Hydrochloric Acid SCHEMBL18690724 0.82 MEN1 (0.39) CHRM2CHRM1CHRM4CHRM3KCNH2
SCHEMBL5685987 0.75 CHRM2 (0.35) CHRM2CHRM1CHRM4CHRM3KCNH2
Hydrochloric Acid SCHEMBL5699165 0.74 MEN1 (0.36) CHRM2CHRM1CHRM4CHRM3KCNH2
Hydrochloric Acid SCHEMBL18690721 0.70 ALDH1A1 (0.33) CHRM2CHRM1CHRM4CHRM3KCNH2
SCHEMBL6049989 0.69 CYP2C19 (0.32) CHRM2CHRM1CHRM4CHRM3KCNH2
SCHEMBL25376 0.68 KEAP1 (0.39) CHRM2CHRM1CHRM4CHRM3KCNH2
SCHEMBL6050060 0.68 KEAP1 (0.39) CHRM2CHRM1CHRM4CHRM3KCNH2
Hydrochloric Acid SCHEMBL25753 0.67 MEN1 (0.39) CHRM2CHRM1CHRM4CHRM3KCNH2
SCHEMBL7324648 0.65 CHRM2 (0.57) CHRM2CHRM1CHRM4CHRM3KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1617790-A1 DRUG-LOADED MEDICAL DEVICE Boston Scientific Scimed, Inc. (US) 2006-01-25 EP disclosed
WO-2004096096-A1 DRUG-LOADED MEDICAL DEVICE SCIMED LIFE SYSTEMS, INC. (US) 2004-11-11 WO disclosed