Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28475131 | 0.79 | GRM8 (0.52) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL28486157 | 0.79 | GRM8 (0.52) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL28486150 | 0.79 | GRM8 (0.52) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL28475140 | 0.79 | GRM8 (0.52) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL5329398 | 0.78 | SLC1A3 (0.44) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL7753733 | 0.77 | CYP1A2 (0.50) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL29291860 | 0.73 | CYP1A2 (0.69) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| Glutamic Acid SCHEMBL1446934 | 0.73 | CYP1A2 (0.69) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| Glutamic Acid SCHEMBL4580128 | 0.73 | CYP1A2 (0.69) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL28602464 | 0.73 | CYP1A2 (0.69) | CYP1A2GRM8GRM6GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179008-B1 | TETRAPEPTIDE REVEALING GEROPROTECTIVE EFFECT, PHARMACOLOGICAL SUBSTANCE ON ITS BASIS, AND THE METHOD OF ITS APPLICATION | OBSCHESTVO S OGRANICHENNOI OTV (RU) | 2006-03-22 | — | — | EP | disclosed |
| US-20050004016-A1 | Method of obtaining peptides with tissue-specific activity and pharmaceutical compositions on their basis | SANKT-PETERBURGSKAYA OBSCHESTVENNAYA, ORGANIZATSIYA "INSTITUT BIOREGULYATSII I GERONTOLOGII SZO RAMN" (RU) | 2005-01-06 | — | — | US | disclosed |
| US-6727227-B1 | CAUSE AN INCREASE IN SUPEROXIDE DISMUTASE ACTIVITY IN SAID SUBJECT | Obschestvo S Ogranichennoi Otvetstven-Nostiju “Klinika Instituta {overscore (B)}ioregulyatsii Gerontologii” (RU) | 2004-04-27 | — | — | US | disclosed |
| EP-1294743-A2 | METHOD OF OBTAINING PEPTIDES WITH TISSUE-SPECIFIC ACTIVITY AND PHARMACEUTICAL COMPOSITIONS ON THEIR BASIS | Sankt-Peterburgskaya Obschestvennaya Organizatsya "Institut Biroregulyatsii i Gerontologii szo Ramn" (RU) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002090380-A1 | TETRAPEPTIDE STIMULATING THE RETINAL FUNCTION AND THE METHOD OF ITS APPLICATION | SANKT-PETERBURGSKAYA OBSCHESTVENNAYA ORGANIZATSIYA 'INSTITUT BIOREGULYATSII I GERONTOLOGII CZO RAMN' (RU) | 2002-11-14 | — | — | WO | disclosed |
| WO-2002000684-A2 | METHOD OF OBTAINING PEPTIDES WITH TISSUE-SPECIFIC ACTIVITY AND PHARMACEUTICAL COMPOSITIONS ON THEIR BASIS | SANKT-PETERBURGSKAYA OBSCHESTVENNAYA OGRANIZATSIYA 'INSTITUT BIOREGULYATSII I GERONTOLOGII CZO RAMN' (RU) | 2002-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004016-A1 | Method of obtaining peptides with tissue-specific activity and pharmaceutical compositions on their basis | VIP, ENPEP, DNPEP | CYP1A2 3186/4885GRM8 827/4885GRM6 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.