Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.50 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30360527 | 0.89 | ALOX15 (0.52) | CYP1A2SLC1A3SLC1A2SLC1A1GRM8 | |
| SCHEMBL28486150 | 0.88 | GRM8 (0.52) | CYP1A2SLC1A3SLC1A2SLC1A1GRM8 | |
| SCHEMBL28486157 | 0.88 | GRM8 (0.52) | CYP1A2SLC1A3SLC1A2SLC1A1GRM8 | |
| SCHEMBL2248721 | 0.87 | CYP1A2 (0.50) | CYP1A2SLC1A3SLC1A2SLC1A1GRM8 | |
| SCHEMBL6812779 | 0.86 | CYP1A2 (0.53) | CYP1A2SLC1A3SLC1A2SLC1A1GRM8 | |
| SCHEMBL10888293 | 0.83 | GABRP (0.48) | CYP1A2SLC1A3SLC1A2SLC1A1GRM8 | |
| SCHEMBL1692048 | 0.83 | ALOX15 (0.52) | CYP1A2SLC1A3SLC1A2SLC1A1GRM8 | |
| SCHEMBL1692053 | 0.83 | ALOX15 (0.52) | CYP1A2SLC1A3SLC1A2SLC1A1GRM8 | |
| SCHEMBL5329398 | 0.81 | SLC1A3 (0.44) | CYP1A2SLC1A3SLC1A2SLC1A1GRM8 | |
| SCHEMBL28475140 | 0.81 | GRM8 (0.52) | CYP1A2SLC1A3SLC1A2SLC1A1GRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073475-A2 | IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS | NYCOMED IMAGING AS (NO) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999055383-A2 | IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS | NYCOMED IMAGING AS (NO) | 1999-11-04 | — | — | WO | disclosed |