SCHEMBL56863

SCHEMBL56863

O=C(Oc1ccccc1Cl)Oc1ccccc1Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTK2B Q14289 1/20 0.51
BCHE P06276 1/20 0.50
LMNA P02545 2/20 0.48
TSHR P16473 1/20 0.48
MAPT P10636 2/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
PKM P14618 1/20 0.47
CXCL8 P10145 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
HPGD P15428 2/20 0.44
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
TP53 P04637 1/20 0.44
HTT P42858 1/20 0.44
ALDH1A1 P00352 1/20 0.43
KDM4E B2RXH2 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29450644 1.00 PTK2B (0.51) PTK2BBCHELMNATSHRMAPT
SCHEMBL97103 0.90 PTK2B (0.45) PTK2BBCHELMNAMAPTMEN1
SCHEMBL9577110 0.88 PTK2B (0.44) PTK2BBCHELMNATSHRMAPT
SCHEMBL11602981 0.88 PTK2B (0.44) PTK2BBCHELMNATSHRMAPT
SCHEMBL6255840 0.88 PTK2B (0.44) PTK2BBCHELMNATSHRMAPT
SCHEMBL982701 0.87 HPGD (0.59) PTK2BBCHETSHRMAPTMEN1
SCHEMBL26622175 0.87 PTK2B (0.46) PTK2BBCHELMNATSHRMAPT
SCHEMBL11013678 0.87 CYP11B1 (0.44) PTK2BBCHELMNAMAPTMEN1
SCHEMBL5141845 0.87 CYP11B1 (0.44) PTK2BBCHELMNAMAPTMEN1
SCHEMBL2947498 0.86 PTK2B (0.51) PTK2BBCHELMNATSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4651 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260117008-A1 Thermoplastic Resin, Preparation Method Therefor, and Use Thereof TOPOLEFIN TECHNOLOGY (QUZHOU) CO., LTD. (CN) 2026-04-30 US claimed
EP-4255960-B1 PROCESS FOR THE PREPARATION OF A POLYCARBONATE USING A HALOGENATED DIARYL CARBONATE COVESTRO DEUTSCHLAND AG (DE) 2025-10-08 EP claimed
CN-118126305-B Thermoplastic resin and preparation method and application thereof 拓烯科技(衢州)有限公司 2024-07-23 CN claimed
CN-118126305-A Thermoplastic resin and preparation method and application thereof 拓烯科技(衢州)有限公司 2024-06-04 CN claimed
CN-115677999-B Polycarbonate and preparation method and application thereof 华为技术有限公司 2024-05-14 CN claimed
CN-115286780-B Copolycarbonate with low-temperature impact resistance, high heat resistance and high refractive index as well as preparation method and application thereof 万华化学集团股份有限公司 2023-12-19 CN claimed
EP-4255960-A1 PROCESS FOR PREPARING A POLYCARBONATE USING A HALOGENATED DIARYL CARBONATE Covestro Deutschland AG (DE) 2023-10-11 EP claimed
CN-114085368-B Polycarbonate and preparation method and application thereof 万华化学集团股份有限公司 2023-08-11 CN claimed
CN-113968963-B Polycarbonate and preparation method and application thereof 万华化学集团股份有限公司 2023-08-11 CN claimed
CN-116507663-A Method for producing polycarbonates using halogenated diaryl carbonates 科思创德国股份有限公司 2023-07-28 CN claimed
US-5698665-A Polycarbonate processes with supercritical carbon dioxide XEROX CORPORATION (US) 1997-12-16 US claimed
EP-0801089-A1 Preparation of branched polycarbonates THE COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 1997-10-15 EP claimed
US-5459225-A Ester interchange in antioxidant presence IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1995-10-17 US claimed
US-5349043-A Transparent, heat resistant, water proof IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-09-20 US claimed
US-5349042-A Ester interchange and dechlorination with carbonation IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-09-20 US claimed
US-5322919-A Transesterification in an inert solvent IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-06-21 US claimed
US-4414230-A BLEND OF A POLYESTER-CARBONATE COPOLYMER AND A POLYESTER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-11-08 US claimed
US-RE31262-E BIS/O-HALOARYL CARBONATE, O-HALOARYL ARYL CARBONATE, DIHYDRIC PHENOL GENERAL ELECTRIC COMPANY (US) 1983-05-31 US claimed
US-4321356-A Transesterification process utilizing as a reactant bis(ortho-haloaryl)carbonates GENERAL ELECTRIC COMPANY (US) 1982-03-23 US claimed
US-4310656-A BIS(O-HALDARYL)CARBONATE AND O-HALOARYLARYL CARBONATE AND DIHYDRIC PHENOL GENERAL ELECTRIC COMPANY (US) 1982-01-12 US claimed