SCHEMBL982701

SCHEMBL982701

COC(=O)Oc1ccccc1Cl

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.59
KDM4E B2RXH2 1/20 0.59
HSD17B10 Q99714 1/20 0.59
BCHE P06276 1/20 0.49
MAPT P10636 2/20 0.46
ALDH1A1 P00352 2/20 0.46
TSHR P16473 1/20 0.46
PTK2B Q14289 1/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
PKM P14618 1/20 0.46
POLB P06746 1/20 0.45
NPSR1 Q6W5P4 1/20 0.44
XIAP P98170 1/20 0.44
ATM Q13315 1/20 0.42
CXCL8 P10145 1/20 0.42
CUL4A Q13619 1/20 0.42
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29450644 0.87 PTK2B (0.51) HPGDKDM4EHSD17B10BCHEMAPT
SCHEMBL56863 0.87 PTK2B (0.51) HPGDKDM4EHSD17B10BCHEMAPT
SCHEMBL11925422 0.85 KDM4E (0.70) HPGDKDM4EHSD17B10BCHEMAPT
SCHEMBL24309423 0.83 HPGD (0.50) HPGDKDM4EHSD17B10MAPTALDH1A1
SCHEMBL5706069 0.83 HPGD (0.43) HPGDKDM4EHSD17B10BCHEMAPT
SCHEMBL5706022 0.83 SLC6A3 (0.59) HPGDKDM4EHSD17B10MAPTALDH1A1
SCHEMBL5705971 0.82 ALDH1A1 (0.46) HPGDKDM4EHSD17B10BCHEMAPT
SCHEMBL15967597 0.82 HPGD (0.42) HPGDKDM4EHSD17B10BCHEMAPT
SCHEMBL5706023 0.80 MAOB (0.54) HPGDKDM4EMAPTALDH1A1KMT2A
SCHEMBL5706021 0.80 SLC6A3 (0.60) HPGDKDM4EHSD17B10MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2540697-B1 METHOD FOR PRODUCING DIARYL CARBONATE ASAHI CHEMICAL IND (JP) 2022-04-20 EP disclosed
US-9233918-B2 Isocyanate production process ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-01-12 US disclosed
EP-1760069-B1 PROCESS FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2013-08-14 EP disclosed
EP-1640357-B1 METHOD FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2011-08-31 EP disclosed
US-20110092731-A1 ISOCYANATE PRODUCTION PROCESS ASAHI KASEI CHEMICALS CORPORATION (JP) 2011-04-21 US disclosed
US-7919644-B2 Process for producing an aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2011-04-05 US disclosed
EP-2275405-A1 PROCESS FOR PRODUCING ISOCYANATE USING DIARYL CARBONATE Asahi Kasei Chemicals Corporation (JP) 2011-01-19 EP disclosed
EP-2275406-A1 PROCESS FOR PRODUCING ISOCYANATE Asahi Kasei Chemicals Corporation (JP) 2011-01-19 EP disclosed
US-7652122-B2 Method for producing an aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-01-26 US disclosed
US-20070185164-A1 Process for producing an aromatic carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2007-08-09 US disclosed
US-5872275-A Process for the producing of aromatic carbonate ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1999-02-16 US disclosed
EP-0855384-A1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATE Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1998-07-29 EP disclosed
US-5696222-A MELT POLYCONDENSATION OF AN AROMATIC DIHYDROXY COMPOUND AND DIPHENYLCARBONATE, THEN ADDING A SPECIFIC CARBONATE OR CARBOCYCLIC ESTER TO FORM TERMINAL BLOCKED POLYCARBONATE TEIJIN LIMITED (JP) 1997-12-09 US disclosed
EP-0764673-A2 Process for the production of polycarbonate TEIJIN LIMITED (JP) 1997-03-26 EP disclosed
EP-0560159-B1 Process for the preparation of aromatic carbonates BAYER AG (DE) 1996-05-08 EP disclosed
EP-0461274-B1 PROCESS FOR CONTINUOUSLY PRODUCING AROMATIC CARBONATE ASAHI CHEMICAL IND (JP) 1994-06-15 EP disclosed
US-5284965-A Process for preparing aromatic carbonates BAYER AKTIENGESELLSCHAFT (DE) 1994-02-08 US disclosed
EP-0560159-A1 Process for the preparation of aromatic carbonates BAYER AG (DE) 1993-09-15 EP disclosed
US-5210268-A Ester interchange, catalysis ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1993-05-11 US disclosed
EP-0461274-A1 PROCESS FOR CONTINUOUSLY PRODUCING AROMATIC CARBONATE Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-12-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070185164-A1 Process for producing an aromatic carbonate TYR, PAH, CYP4A11 HPGD 4006/4885KDM4E 214/4885HSD17B10 446/4885
US-20110092731-A1 ISOCYANATE PRODUCTION PROCESS CPS1, PHGDH, APEH HPGD 265/4885KDM4E 1003/4885HSD17B10 90/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.