Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | TEAD1 | P28347 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5686985 | 1.00 | HTR2C (0.37) | HTR2CTEAD1CNR1DGAT1SOAT1 | |
| SCHEMBL5686524 | 0.86 | SLC6A2 (0.31) | ESR2 | |
| SCHEMBL5686521 | 0.86 | SLC6A2 (0.31) | ESR2 | |
| SCHEMBL5683809 | 0.86 | HTR2C (0.35) | HTR2CTEAD1CNR1DGAT1SOAT1 | |
| SCHEMBL5683810 | 0.86 | HTR2C (0.35) | HTR2CTEAD1CNR1DGAT1SOAT1 | |
| SCHEMBL5683503 | 0.85 | EPHX2 (0.34) | TEAD1 | |
| SCHEMBL5683511 | 0.85 | EPHX2 (0.34) | TEAD1 | |
| SCHEMBL5683347 | 0.84 | ALDH1A1 (0.43) | HTR2CTEAD1CNR1IDO1 | |
| SCHEMBL5683343 | 0.84 | ALDH1A1 (0.43) | HTR2CTEAD1CNR1IDO1 | |
| SCHEMBL5684503 | 0.84 | SLC6A3 (0.32) | IDO1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067179-B1 | Fused ring compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1201632-B1 | FUSED RING COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2006-03-29 | — | — | EP | disclosed |
| EP-1201632-A1 | FUSED RING COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-02 | — | — | EP | disclosed |