Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.52 |
| ▸ | PYGL | P06737 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5689048 | 1.00 | GRIN2B (0.52) | GRIN2BPYGLKDRRAB9ANPC1 | |
| SCHEMBL6058909 | 0.86 | GRIN2B (0.53) | GRIN2BPYGLKDRRAB9ANPC1 | |
| SCHEMBL5688688 | 0.84 | PTK2 (0.53) | GRIN2BPYGLRAB9ATRPV1L3MBTL1 | |
| SCHEMBL5689277 | 0.84 | PTK2 (0.53) | GRIN2BPYGLRAB9ATRPV1L3MBTL1 | |
| SCHEMBL5689653 | 0.84 | PTK2 (0.53) | GRIN2BPYGLRAB9ATRPV1L3MBTL1 | |
| SCHEMBL9888659 | 0.82 | DEGS1 (0.51) | GRIN2BKDRRAB9ANPC1PAX8 | |
| SCHEMBL2645077 | 0.78 | PYGL (0.46) | GRIN2BPYGLKDRRAB9ANPC1 | |
| SCHEMBL1445386 | 0.78 | PYGL (0.46) | GRIN2BPYGLKDRRAB9ANPC1 | |
| SCHEMBL3923056 | 0.76 | RAB9A (0.48) | GRIN2BKDRRAB9ANPC1PAX8 | |
| Hydrochloric Acid SCHEMBL6059862 | 0.76 | MAPK1 (0.45) | GRIN2BKDRRAB9ANPC1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938476-B1 | PROCESS FOR SUBSTITUTED PYRIDINES | PFIZER (US) | 2006-03-08 | — | — | EP | disclosed |
| US-6291489-B1 | USEFUL IN THE SYNTHESIS OF CERTAIN .BETA.-ADRENERGIC RECEPTOR AGONISTS | PFIZER INC. | 2001-09-18 | — | — | US | disclosed |
| US-6001856-A | β-adrenergic agonists to reduce a wasting condition | PFIZER INC. (US) | 1999-12-14 | — | — | US | disclosed |
| EP-0887079-A1 | Beta-Adrenergic agonists to reduce a wasting condition | PFIZER INC. (US) | 1998-12-30 | — | — | EP | disclosed |