Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | FABP7 | O15540 | 1/20 | 0.56 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1868801 | 0.93 | ALDH1A1 (0.63) | ALDH1A1ATMFABP7FABP5NPC1 | |
| SCHEMBL1871228 | 0.93 | ALDH1A1 (0.62) | ALDH1A1ATMFABP7FABP5NPC1 | |
| SCHEMBL112518 | 0.93 | ALDH1A1 (0.62) | ALDH1A1ATMFABP7FABP5NPC1 | |
| SCHEMBL28954975 | 0.90 | ALDH1A1 (0.57) | ALDH1A1ATMFABP7FABP5NPC1 | |
| SCHEMBL8024062 | 0.88 | ALDH1A1 (0.72) | ALDH1A1NPC1RAB9ASMN1; SMN2LTA4H | |
| SCHEMBL19721780 | 0.88 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9APOLBSMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL28355876 | 0.85 | NPC1 (0.64) | ALDH1A1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL24063952 | 0.84 | ALDH1A1 (0.72) | ALDH1A1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL22028109 | 0.84 | LTA4H (0.58) | ALDH1A1ATMFABP7FABP5NPC1 | |
| SCHEMBL22028110 | 0.84 | LTA4H (0.58) | ALDH1A1ATMFABP7FABP5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654197-A1 | CARRIER BASED ON GRANULES PRODUCED FROM PYROGENICALLY PREPARED SILICON DIOXIDES | Degussa AG (DE) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005016823-A1 | CARRIER BASED ON GRANULES PRODUCED FROM PYROGENICALLY PREPARED SILICON DIOXIDES | DEGUSSA AG (DE) | 2005-02-24 | — | — | WO | disclosed |