Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.65 |
| ▸ | PPARG | P37231 | 12/20 | 0.58 |
| ▸ | PPARD | Q03181 | 13/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5691366 | 0.87 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL5367466 | 0.87 | PPARA (0.49) | PPARAPPARGPPARD | |
| SCHEMBL5367477 | 0.81 | PPARA (0.44) | PPARAPPARGPPARD | |
| SCHEMBL3233074 | 0.81 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL5543269 | 0.81 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL17680422 | 0.81 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL543815 | 0.81 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL1670312 | 0.80 | PPARA (0.69) | PPARAPPARGPPARD | |
| SCHEMBL4993002 | 0.80 | PPARA (0.69) | PPARAPPARGPPARD | |
| SCHEMBL24328379 | 0.80 | PPARA (0.66) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638926-A1 | 2-ETHOXY-3-PHENYLPROPIONIC ACID DERIVATIVES FOR THE TREATMENT OF LIPID DISORDERS | Astrazeneca AB (SE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004113276-A1 | 2-ETHOXY-3-PHENYLPROPIONIC ACID DERIVATIVES FOR THE TREATMENT OF LIPID DISORDERS | ASTRAZENECA AB (SE) | 2004-12-29 | — | — | WO | disclosed |