Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PAM | P19021 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391481 | 0.89 | TSHR (0.71) | TSHRHCAR2LPAR1CRHBPCRHR2 | |
| SCHEMBL112612 | 0.89 | TSHR (0.71) | TSHRHCAR2LPAR1CRHBPCRHR2 | |
| SCHEMBL13046507 | 0.89 | TSHR (0.71) | TSHRHCAR2LPAR1CRHBPCRHR2 | |
| Formic Acid SCHEMBL11016171 | 0.84 | TSHR (0.63) | TSHRHCAR2LPAR1CRHBPCRHR2 | |
| SCHEMBL14088113 | 0.83 | TSHR (0.54) | TSHRHCAR2LPAR1KLK7ALDH1A1 | |
| SCHEMBL3395745 | 0.79 | KLK7 (0.61) | TSHRKLK7ALDH1A1L3MBTL1CNR2 | |
| SCHEMBL28312880 | 0.78 | TSHR (0.68) | TSHRKLK7ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL3395537 | 0.77 | TSHR (0.62) | TSHRCRHBPCRHR2KLK7ALDH1A1 | |
| SCHEMBL3393812 | 0.77 | TSHR (0.62) | TSHRCRHBPCRHR2KLK7ALDH1A1 | |
| SCHEMBL14088117 | 0.77 | TSHR (0.50) | TSHRHCAR2LPAR1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654197-A1 | CARRIER BASED ON GRANULES PRODUCED FROM PYROGENICALLY PREPARED SILICON DIOXIDES | Degussa AG (DE) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005016823-A1 | CARRIER BASED ON GRANULES PRODUCED FROM PYROGENICALLY PREPARED SILICON DIOXIDES | DEGUSSA AG (DE) | 2005-02-24 | — | — | WO | disclosed |