Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 11/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13046507 | 0.89 | TSHR (0.71) | KLK7TSHRCNR2ALDH1A1L3MBTL1 | |
| SCHEMBL112612 | 0.89 | TSHR (0.71) | KLK7TSHRCNR2ALDH1A1L3MBTL1 | |
| SCHEMBL3391481 | 0.89 | TSHR (0.71) | KLK7TSHRCNR2ALDH1A1L3MBTL1 | |
| SCHEMBL11460504 | 0.84 | KLK7 (0.64) | KLK7TSHRCNR2CNR1ALDH1A1 | |
| Formic Acid SCHEMBL11016171 | 0.83 | TSHR (0.63) | KLK7TSHRCNR2ALDH1A1L3MBTL1 | |
| SCHEMBL14088113 | 0.82 | TSHR (0.54) | KLK7TSHRALDH1A1 | |
| SCHEMBL3497340 | 0.82 | KLK7 (0.60) | KLK7TSHRCNR2CNR1POLB | |
| SCHEMBL5676693 | 0.80 | KLK7 (0.57) | KLK7TSHRALDH1A1POLB | |
| SCHEMBL14088226 | 0.80 | TSHR (0.48) | KLK7TSHR | |
| Phenylpropanol SCHEMBL5690153 | 0.79 | TSHR (0.58) | KLK7TSHRCNR2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569013-B2 | Penicillin-G acylases | CODEXIS, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-8569013-B2 | Penicillin-G acylases | CODEXIS, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-8569013-B2 | Penicillin-G acylases | CODEXIS, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20120270282-A1 | PENICILLIN-G ACYLASES | CODEXIS, INC. (US) | 2012-10-25 | — | — | US | disclosed |
| US-20120270282-A1 | PENICILLIN-G ACYLASES | CODEXIS, INC. (US) | 2012-10-25 | — | — | US | disclosed |
| US-20120270282-A1 | PENICILLIN-G ACYLASES | CODEXIS, INC. (US) | 2012-10-25 | — | — | US | disclosed |
| US-8247192-B2 | Penicillin-G acylases | CODEXIS, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| US-8247192-B2 | Penicillin-G acylases | CODEXIS, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| US-8247192-B2 | Penicillin-G acylases | CODEXIS, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| US-20100143968-A1 | PENICILLIN-G ACYLASES | CODEXIS, INC. (US) | 2010-06-10 | — | — | US | disclosed |
| US-20100143968-A1 | PENICILLIN-G ACYLASES | CODEXIS, INC. (US) | 2010-06-10 | — | — | US | disclosed |
| US-20100143968-A1 | PENICILLIN-G ACYLASES | CODEXIS, INC. (US) | 2010-06-10 | — | — | US | disclosed |
| WO-2010054319-A2 | PENICILLIN-G ACYLASES | CODEXIS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010054319-A2 | PENICILLIN-G ACYLASES | CODEXIS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270282-A1 | PENICILLIN-G ACYLASES | PGLS, PNP, NAAA | KLK7 2105/4885TSHR 4126/4885CNR2 4796/4885 |
| US-20100143968-A1 | PENICILLIN-G ACYLASES | PGLS, PNP, NAAA | KLK7 2105/4885TSHR 4126/4885CNR2 4796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.