Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 3/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5690461 | 0.91 | HDAC4 (0.37) | HDAC4KMT2APOLBSMN1; SMN2MEN1 | |
| SCHEMBL1904196 | 0.82 | CHRM2 (0.50) | KMT2APOLBSMN1; SMN2MEN1PRCP | |
| SCHEMBL290573 | 0.79 | OPRM1 (0.46) | HDAC4KMT2APOLBSMN1; SMN2MEN1 | |
| SCHEMBL1612406 | 0.76 | HDAC4 (0.47) | HDAC4KMT2AMEN1ALDH1A1APOBEC3A | |
| SCHEMBL27296884 | 0.75 | HDAC4 (0.46) | HDAC4KMT2AMEN1ALDH1A1APOBEC3A | |
| SCHEMBL9270722 | 0.69 | OPRM1 (0.47) | HDAC4KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL290754 | 0.69 | HDAC4 (0.50) | HDAC4KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL27774530 | 0.69 | HDAC4 (0.50) | HDAC4KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL1953126 | 0.67 | AKR1C1 (0.50) | HDAC4KMT2ASMN1; SMN2MEN1HTT | |
| SCHEMBL28279369 | 0.65 | PRCP (0.39) | HDAC4POLBSMN1; SMN2PRCPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1424321-B1 | Synthesis of optically active cyclohexylphenylglycolate esters | SEPRACOR INC (US) | 2006-07-05 | — | — | EP | claimed |
| EP-1424321-A1 | Synthesis of optically active cyclohexylphenylglycolate esters | Sepracor, Inc. (US) | 2004-06-02 | — | — | EP | claimed |
| EP-1185498-A2 | SYNTHESIS OF OPTICALLY ACTIVE CYCLOHEXYLPHENYLGLYCOLIC ACID AND ITS ESTERS | Sepracor Inc. (US) | 2002-03-13 | — | — | EP | claimed |
| US-6140529-A | Synthesis of optically active cyclohexylphenylglycolate esters | SEPRACOR INC. (US) | 2000-10-31 | — | — | US | claimed |
| WO-2000023414-A2 | SYNTHESIS OF OPTICALLY ACTIVE CYCLOHEXYLPHENYLGLYCOLIC ACID AND ITS ESTERS | SEPRACOR INC. (US) | 2000-04-27 | — | — | WO | claimed |
| EP-1424321-B1 | Synthesis of optically active cyclohexylphenylglycolate esters | SEPRACOR INC (US) | 2006-07-05 | — | — | EP | disclosed |
| EP-1642883-A2 | Optically active cyclohexylphenylglycolate esters | SEPRACOR Inc (US) | 2006-04-05 | — | — | EP | disclosed |
| EP-1424321-A1 | Synthesis of optically active cyclohexylphenylglycolate esters | Sepracor, Inc. (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-1185498-A2 | SYNTHESIS OF OPTICALLY ACTIVE CYCLOHEXYLPHENYLGLYCOLIC ACID AND ITS ESTERS | Sepracor Inc. (US) | 2002-03-13 | — | — | EP | disclosed |
| US-6140529-A | Synthesis of optically active cyclohexylphenylglycolate esters | SEPRACOR INC. (US) | 2000-10-31 | — | — | US | disclosed |
| US-6090971-A | Resolution process for cyclohexylphenyl glycolic acid | SEPRACOR INC. (US) | 2000-07-18 | — | — | US | disclosed |
| WO-2000023414-A2 | SYNTHESIS OF OPTICALLY ACTIVE CYCLOHEXYLPHENYLGLYCOLIC ACID AND ITS ESTERS | SEPRACOR INC. (US) | 2000-04-27 | — | — | WO | disclosed |
| US-5973182-A | Carbonate Intermediates useful in the preparation of optically active cyclohexylphenylglycolate esters | SEPRACOR INC. (US) | 1999-10-26 | — | — | US | disclosed |