Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 6/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 10/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ITGAV | P06756 | 3/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5690673 | 0.90 | ITGA4 (0.65) | ITGA4ITGB1ITGA5L3MBTL1ITGAV | |
| SCHEMBL7163529 | 0.84 | ITGA4 (0.67) | ITGA4ITGB1ITGA5L3MBTL1ITGAV | |
| SCHEMBL3860100 | 0.84 | ITGA4 (0.67) | ITGA4ITGB1ITGA5L3MBTL1ITGAV | |
| SCHEMBL6712483 | 0.82 | ITGA4 (0.57) | ITGA4ITGB1ITGA5L3MBTL1ITGAV | |
| SCHEMBL6709349 | 0.80 | ITGA4 (0.49) | ITGA4ITGB1ITGA5L3MBTL1ITGAV | |
| SCHEMBL6709261 | 0.80 | ITGA4 (0.51) | ITGA4ITGB1ITGA5ITGB7L3MBTL1 | |
| SCHEMBL3848814 | 0.80 | ITGA4 (0.53) | ITGA4ITGB1ITGA5ITGB7CACNA1B | |
| SCHEMBL7071151 | 0.80 | ITGA4 (0.58) | ITGA4ITGB1ITGA5L3MBTL1ITGA2 | |
| SCHEMBL3851600 | 0.80 | ITGA4 (0.59) | ITGA4ITGB1ITGA5ITGB7CACNA1B | |
| SCHEMBL7314087 | 0.79 | ITGA4 (0.57) | ITGA4ITGB1ITGA5L3MBTL1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001974-B1 | 4-AMINO-PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2006-05-24 | — | — | EP | claimed |