Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5690361 | 0.92 | ENPP3 (0.39) | MAPTTP53TRPV1ALDH1A1ENPP3 | |
| SCHEMBL5690598 | 0.88 | MAPT (0.37) | MAPTTP53TRPV1ALDH1A1ENPP3 | |
| SCHEMBL5690230 | 0.84 | MAPT (0.38) | MAPTTP53TRPV1ALDH1A1ENPP3 | |
| SCHEMBL5690619 | 0.81 | TRPV1 (0.39) | MAPTTP53TRPV1ALDH1A1ENPP3 | |
| SCHEMBL5690666 | 0.81 | MAPT (0.37) | MAPTTP53TRPV1ALDH1A1ENPP3 | |
| SCHEMBL5690785 | 0.80 | ENPP3 (0.36) | MAPTTP53TRPV1ALDH1A1ENPP3 | |
| SCHEMBL3858269 | 0.79 | PTGES (0.37) | ALDH1A1KMT2A | |
| SCHEMBL5691919 | 0.78 | MAPT (0.36) | MAPTTP53TRPV1ALDH1A1ENPP3 | |
| SCHEMBL5690856 | 0.78 | ENPP3 (0.35) | MAPTTP53TRPV1ALDH1A1ENPP3 | |
| SCHEMBL5690950 | 0.77 | ENPP3 (0.38) | MAPTTP53TRPV1ALDH1A1ENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001974-B1 | 4-AMINO-PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2006-05-24 | — | — | EP | claimed |