Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL571245 | 0.92 | TSHR (0.56) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL28686046 | 0.92 | TSHR (0.56) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL560829 | 0.88 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL1073214 | 0.88 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL4577010 | 0.88 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL1068956 | 0.88 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL27925082 | 0.84 | DAO (0.47) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL561248 | 0.84 | DAO (0.47) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoyl Formic Acid SCHEMBL16044060 | 0.84 | CES2 (0.50) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL28702834 | 0.83 | TSHR (0.54) | TSHRDAONAPRTSRD5A2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290624-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118290623-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118290625-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-117924558-A | Solid catalyst component for olefin polymerization, preparation method and application thereof | 中国石油化工股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117924557-A | Prepolymerized catalyst for olefin polymerization, preparation method and application thereof | 中国石油化工股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117924559-A | Solid catalyst component for olefin polymerization and application thereof | 中国石油化工股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117756970-A | Catalyst for butene-1 polymerization and application thereof | 中国石油化工股份有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-114478846-B | Carrier of catalyst with olefin polymerization catalyzing function, preparation method and application thereof, olefin polymerization catalyst and application thereof | 中国石油化工股份有限公司 | 2023-09-08 | — | — | CN | claimed |
| CN-112175119-B | Solid catalyst component for olefin polymerization, process for producing the same, olefin polymerization catalyst, and process for olefin polymerization | 中国石油化工股份有限公司 | 2023-08-15 | — | — | CN | claimed |
| CN-112175117-B | Solid catalyst component for olefin polymerization, process for producing the same, catalyst for olefin polymerization, and process for olefin polymerization | 中国石油化工股份有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-114085301-B | Solid catalyst component for preparing olefin polymer and application thereof | 中国石油化工股份有限公司 | 2023-05-09 | — | — | CN | claimed |
| CN-114478846-A | Carrier of catalyst with function of catalyzing olefin polymerization, preparation method and application of carrier, olefin polymerization catalyst and application of olefin polymerization catalyst | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114085301-A | Solid catalyst component for preparing olefin polymer and application thereof | 中国石油化工股份有限公司 | 2022-02-25 | — | — | CN | claimed |
| CN-113773423-A | Solid catalyst component for preparing olefin polymer and application thereof | 中国石油化工股份有限公司 | 2021-12-10 | — | — | CN | claimed |
| CN-113444189-A | Catalyst for olefin polymerization and application thereof | 中国石油化工股份有限公司 | 2021-09-28 | — | — | CN | claimed |
| CN-118290625-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118290624-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| WO-2012017038-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2012-02-09 | — | — | WO | disclosed |
| EP-2225288-A1 | SELF-LIMITING CATALYST COMPOSITION WITH BIDENTATE INTERNAL DONOR | Dow Global Technologies Inc. (US) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009085649-A1 | SELF-LIMITING CATALYST COMPOSITION WITH BIDENTATE INTERNAL DONOR | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-07-09 | — | — | WO | disclosed |