SCHEMBL5692913

SCHEMBL5692913

CC/C(=C\c1ccc(O)cc1)c1ccc(C(=O)O)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.80
ESR2 Q92731 3/20 0.80
ALDH1A1 P00352 3/20 0.54
GLA P06280 1/20 0.54
POLB P06746 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
CA2 P00918 2/20 0.53
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA3 P07451 1/20 0.53
TYR P14679 1/20 0.53
DRD1 P21728 1/20 0.53
CA4 P22748 1/20 0.53
CA6 P23280 1/20 0.53
CA5A P35218 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53
CA5B Q9Y2D0 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5692915 1.00 ESR1 (0.80) ESR1ESR2ALDH1A1GLAPOLB
SCHEMBL574346 0.89 ESR1 (1.00) ESR1ESR2ALDH1A1DRD1PTGS1
SCHEMBL9113341 0.89 ESR1 (1.00) ESR1ESR2ALDH1A1DRD1PTGS1
SCHEMBL8393141 0.84 ESR1 (0.82) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL3988713 0.84 ESR1 (0.82) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL8393139 0.84 ESR1 (0.82) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL3988719 0.84 ESR1 (0.82) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL9622832 0.84 ESR1 (0.82) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL5692883 0.78 CXCL12 (0.62) ALDH1A1POLBTDP1CA2CA12
SCHEMBL5692880 0.78 CXCL12 (0.62) ALDH1A1POLBTDP1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0905164-B1 Liquid crystalline polyester compositions and their uses NIPPON MITSUBISHI OIL CORP (JP) 2006-05-03 EP disclosed
US-5989758-A EXHIBIT A LIQUID CRYSTALLINE PHASE AT TIME OF FUSION, WHICH CAN BE FIXED UPON COOLING BELOW THE LIQUID CRYSTALLINE TRANSITION TEMPERATURE; SPECIFIC MONOMERS 4,4'-STILBENEDIOLS, CATECHOLS, AND 4'-HYDROXY-4-STILBENECARBOXYLIC ACIDS NIPPON OIL COMPANY, LIMITED (JP) 1999-11-23 US disclosed
EP-0905164-A2 Liquid crystalline polyesters, their composition, and their uses NIPPON OIL CO., LTD. (JP) 1999-03-31 EP disclosed