Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 6/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 2/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6623864 | 0.81 | PDPK1 (0.49) | SCN9AP2RX4CA1CA2CA9 | |
| SCHEMBL29608350 | 0.78 | ADORA2A (0.47) | CA1CA2CA9PDPK1ADORA2A | |
| SCHEMBL1093747 | 0.78 | ADORA2A (0.47) | CA1CA2CA9PDPK1ADORA2A | |
| SCHEMBL30130504 | 0.77 | ALDH1A1 (0.39) | CA1CA2CA9PDPK1ADORA2A | |
| SCHEMBL28816427 | 0.77 | LOXL2 (0.45) | P2RX4CA2CA9PDPK1ADORA2A | |
| SCHEMBL3838065 | 0.77 | ALDH1A1 (0.39) | CA1CA2CA9PDPK1ADORA2A | |
| Hydrochloric Acid SCHEMBL5692845 | 0.77 | ADORA2A (0.46) | CA1CA2CA9PDPK1ADORA2A | |
| Hydrochloric Acid SCHEMBL5692830 | 0.77 | ADORA2A (0.46) | CA1CA2CA9PDPK1ADORA2A | |
| SCHEMBL5692967 | 0.77 | SCN9A (0.47) | SCN9ASOS1P2RX4CA2CA9 | |
| SCHEMBL11154755 | 0.75 | SYK (0.43) | SCN9ASYKTHRATHRBPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638553-A1 | NEW USE I | BIOVITRUM AB (SE) | 2006-03-29 | — | — | EP | claimed |
| WO-2004112784-A1 | NEW USE I | BIOVITRUM AB (SE) | 2004-12-29 | — | — | WO | claimed |