SCHEMBL5693118

SCHEMBL5693118

C1=CC=CNC=C1.CS(=O)(=O)O

nearest known ligand 0.33

Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.33
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
THRB P10828 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
CASP1 P29466 1/20 0.31
RECQL P46063 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28044265 0.75
Oxygen SCHEMBL27468735 0.73
SCHEMBL22434925 0.73
SCHEMBL27879484 0.73
SCHEMBL28184335 0.73
SCHEMBL22993 0.73
Ethane SCHEMBL28239037 0.70
Bromide SCHEMBL9054418 0.69
Ammonia Solution, Strong SCHEMBL22117290 0.69
Hydrochloric Acid SCHEMBL10373824 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119522874-A Use of inhibitors for improving placental hypertrophy in cloned animals 内蒙古大学 2025-02-28 CN claimed
CN-101862295-A Aggregate having enhanced deformability and including at least three amphipatic substances IDEA AG 2010-10-20 CN claimed
CN-120092017-A Chimeric antigen receptor domains 提克瓦阿洛塞尔私人有限公司 2025-06-03 CN disclosed
CN-120076831-A Anti-ROR 1 antibodies and antibody conjugates, compositions comprising anti-ROR 1 antibodies or antibody conjugates, and methods of making and using anti-ROR 1 antibodies and antibody conjugates 苏特罗生物制药公司 2025-05-30 CN disclosed
CN-116157403-B Morphology of treasiril and method for producing same 海南先声再明医药股份有限公司 2025-04-25 CN disclosed
CN-119522874-A Use of inhibitors for improving placental hypertrophy in cloned animals 内蒙古大学 2025-02-28 CN disclosed
CN-111837146-B G1T38 excellent dosing regimen G1治疗公司 2024-10-15 CN disclosed
CN-110913861-B Morphological forms of G1T38 and methods of making the same G1治疗公司 2024-01-09 CN disclosed
CN-112955162-B Adipocyte-mediated delivery of anticancer therapeutic agents 北卡罗莱纳州立大学 2023-10-13 CN disclosed
CN-116157403-A Morphology of treasiril and method for producing same G1治疗公司 2023-05-23 CN disclosed
EP-1656352-A1 6-(2,2,2-TRIFLUOROETHYLAMINO)-7-CHLORO-2,3,4,5-TETRAHYDRO-1H-BENZO d AZEPINE AS A 5-HT sb 2c /sb RECEPTOR AGONIST ELI LILLY AND COMPANY (US) 2006-05-17 EP disclosed
WO-2005019180-A1 6-(2,2,2-TRIFLUOROETHYLAMINO)-7-CHLORO-2,3,4,5-TETRAHYDRO-1H-BENZO[d]AZEPINE AS A 5-HT2c RECEPTOR AGONIST ELI LILLY AND COMPANY (US) 2005-03-03 WO disclosed