Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3053052 | 1.00 | CYP1A2 (0.46) | CYP1A2MEN1KMT2ATDP1EGFR | |
| SCHEMBL3072447 | 1.00 | CYP1A2 (0.46) | CYP1A2MEN1KMT2ATDP1EGFR | |
| SCHEMBL3072451 | 1.00 | CYP1A2 (0.46) | CYP1A2MEN1KMT2ATDP1EGFR | |
| SCHEMBL3053051 | 1.00 | CYP1A2 (0.46) | CYP1A2MEN1KMT2ATDP1EGFR | |
| SCHEMBL3062714 | 0.87 | CYP1A2 (0.49) | CYP1A2MEN1KMT2ATDP1EGFR | |
| SCHEMBL3073240 | 0.87 | POLB (0.43) | CYP1A2MEN1KMT2ATDP1EGFR | |
| SCHEMBL5693171 | 0.83 | LMNA (0.50) | MEN1KMT2ATDP1L3MBTL1POLB | |
| SCHEMBL3070948 | 0.78 | CYP1A2 (0.53) | CYP1A2MEN1KMT2ATDP1HDAC3 | |
| SCHEMBL3070951 | 0.78 | CYP1A2 (0.53) | CYP1A2MEN1KMT2ATDP1HDAC3 | |
| SCHEMBL3070944 | 0.78 | CYP1A2 (0.53) | CYP1A2MEN1KMT2ATDP1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658260-A1 | BUTENOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND USE FOR THE TREATMENT OF DYSLIPIDAEMIA, ATHEROSCLEROSIS AND DIABETES | Merk Patent Gmbh (DE) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005014521-A1 | BUTENOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND USE FOR THE TREATMENT OF DYSLIPIDAEMIA, ATHEROSCLEROSIS AND DIABETES | MERK PATENT GMBH (DE) | 2005-02-17 | — | — | WO | disclosed |