Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 16/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5693249 | 0.85 | PTGS2 (0.60) | PTGS2CYP2C9PTGS1 | |
| SCHEMBL12629112 | 0.74 | ALOX5 (0.80) | ALOX5PTGS2CYP2C9PTGS1 | |
| SCHEMBL14280456 | 0.72 | ALOX5 (0.76) | ALOX5PTGS2CYP2C9PTGS1AOC3 | |
| SCHEMBL17369546 | 0.71 | ALOX5 (1.00) | ALOX5PTGS2CYP2C9PTGS1 | |
| SCHEMBL16425767 | 0.69 | ALOX5 (0.70) | ALOX5PTGS2CYP2C9PTGS1AOC3 | |
| SCHEMBL4017911 | 0.69 | PTGS2 (0.43) | ALOX5PTGS2CYP2C9PTGS1 | |
| Dimethylamine SCHEMBL9204674 | 0.68 | ALOX5 (0.69) | ALOX5PTGS2CYP2C9PTGS1AOC3 | |
| SCHEMBL5693528 | 0.64 | PTGS2 (0.61) | ALOX5PTGS2CYP2C9PTGS1 | |
| SCHEMBL5693296 | 0.62 | PTGS2 (0.47) | ALOX5PTGS2PTGS1 | |
| SCHEMBL8420247 | 0.62 | CYP2C9 (0.71) | ALOX5PTGS2CYP2C9PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1384477-B1 | UTILIZATION OF PYRAZOLINE DERIVATIVES IN THE PREPARATION OF A MEDICAMENT FOR THE PREVENTION AND/OR TREATMENT OF PROLIFERATIVE CELL DISEASES | ESTEVE LABOR DR (ES) | 2006-05-24 | — | — | EP | claimed |