Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13862890 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2HSD17B10TGFBR1TSHRKDM4E | |
| SCHEMBL20216160 | 0.82 | SMN1; SMN2 (0.37) | SMN1; SMN2HSD17B10TGFBR1ALDH1A1 | |
| SCHEMBL5693436 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2HSD17B10TGFBR1TSHRKDM4E | |
| SCHEMBL19176636 | 0.79 | SMN1; SMN2 (0.35) | SMN1; SMN2HSD17B10TGFBR1ALDH1A1 | |
| SCHEMBL10962612 | 0.79 | SMN1; SMN2 (0.33) | SMN1; SMN2HSD17B10 | |
| SCHEMBL183583 | 0.79 | TGFBR1 (0.37) | SMN1; SMN2HSD17B10TGFBR1ALDH1A1 | |
| SCHEMBL5693540 | 0.77 | KDM4E (0.38) | SMN1; SMN2HSD17B10TGFBR1KDM4E | |
| SCHEMBL18897130 | 0.76 | TSHR (0.33) | SMN1; SMN2HSD17B10TGFBR1TSHRALDH1A1 | |
| SCHEMBL20269674 | 0.76 | SMN1; SMN2 (0.38) | SMN1; SMN2HSD17B10TSHR | |
| SCHEMBL3232710 | 0.76 | TGFBR1 (0.36) | SMN1; SMN2HSD17B10TGFBR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487882-B1 | BASE POLYMER OBTAINED BY HYDROGENATION | STOCKHAUSEN CHEM FAB GMBH (DE) | 2006-05-24 | — | — | EP | disclosed |
| US-20050215756-A1 | Basic polymer obtained by hydrogenation | STOCKHAUSEN GMBH (DE) | 2005-09-29 | — | — | US | disclosed |
| EP-1487882-A1 | BASE POLYMER OBTAINED BY HYDROGENATION | Stockhausen GmbH (DE) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003080682-A1 | BASE POLYMER OBTAINED BY HYDROGENATION | STOCKHAUSEN GMBH (DE) | 2003-10-02 | — | — | WO | disclosed |