Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | FPR3 | P25089 | 3/20 | 0.33 |
| ▸ | FPR2 | P25090 | 3/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13862890 | 0.87 | SMN1; SMN2 (0.45) | KDM4ESMN1; SMN2HSD17B10TGFBR1TDP1 | |
| SCHEMBL20216160 | 0.82 | SMN1; SMN2 (0.37) | SMN1; SMN2HSD17B10TGFBR1 | |
| SCHEMBL183583 | 0.82 | TGFBR1 (0.37) | SMN1; SMN2HSD17B10TGFBR1 | |
| SCHEMBL5693436 | 0.80 | SMN1; SMN2 (0.40) | KDM4ESMN1; SMN2HSD17B10TGFBR1 | |
| SCHEMBL15153924 | 0.79 | KDM4E (0.40) | KDM4ESMN1; SMN2HSD17B10CYP2D6FPR3 | |
| SCHEMBL21172271 | 0.79 | KDM4E (0.45) | KDM4ESMN1; SMN2HSD17B10CYP2D6FPR3 | |
| SCHEMBL819336 | 0.79 | TDP1 (0.35) | SMN1; SMN2HSD17B10TGFBR1TDP1 | |
| SCHEMBL3232710 | 0.79 | TGFBR1 (0.36) | KDM4ESMN1; SMN2HSD17B10TGFBR1TDP1 | |
| SCHEMBL13463180 | 0.79 | KDM4E (0.43) | KDM4ESMN1; SMN2HSD17B10CYP2D6FPR3 | |
| SCHEMBL19176636 | 0.78 | SMN1; SMN2 (0.35) | SMN1; SMN2HSD17B10TGFBR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487882-B1 | BASE POLYMER OBTAINED BY HYDROGENATION | STOCKHAUSEN CHEM FAB GMBH (DE) | 2006-05-24 | — | — | EP | disclosed |
| US-20050215756-A1 | Basic polymer obtained by hydrogenation | STOCKHAUSEN GMBH (DE) | 2005-09-29 | — | — | US | disclosed |
| EP-1487882-A1 | BASE POLYMER OBTAINED BY HYDROGENATION | Stockhausen GmbH (DE) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003080682-A1 | BASE POLYMER OBTAINED BY HYDROGENATION | STOCKHAUSEN GMBH (DE) | 2003-10-02 | — | — | WO | disclosed |